公开(公告)号：US11306058B2

公开(公告)日：2022-04-19

申请号：US16618036

申请日：2018-05-31

申请人： IDORSIA PHARMACEUTICALS LTD

发明人： Vitor Oliveira ,  Ivan Pogorelic ,  Jean-Paul Roduit

IPC分类号： C07D211/40 ,  C07D211/46 ,  A61K9/48 ,  A61P3/06 ,  A61P43/00 ,  A61P25/00 ,  A61P35/00 ,  A61K31/445

摘要： The invention relates to a crystalline form of [(2R,3S,4R,5S)-1-butyl-2-(hydroxymethyl)-piperidine-3,4,5-triol, processes for the preparation thereof, pharmaceutical compositions containing such a crystalline form, and its use as a medicament, especially as glycolipid biosynthesis inhibitor.

公开(公告)号：US11713297B2

公开(公告)日：2023-08-01

申请号：US17479341

申请日：2021-09-20

申请人： IDORSIA PHARMACEUTICALS LTD

发明人： Vitor Oliveira ,  Ivan Pogorelic ,  Jean-Paul Roduit

IPC分类号： A61K9/48 ,  C07D211/40

CPC分类号： C07D211/40 ,  A61K9/4858 ,  C07B2200/13

摘要： The invention relates to a crystalline form of [(2R,3S,4R,5S)-1-butyl-2-(hydroxymethyl)-piperidine-3,4,5-triol, processes for the preparation thereof, pharmaceutical compositions containing such a crystalline form, and its use as a medicament, especially as glycolipid biosynthesis inhibitor.