-
1.发明公开公开(公告)号：US20240207360A1
公开(公告)日：2024-06-27
申请号：US18412403
申请日：2024-01-12
发明人： Chulhee CHOI , Nambin YIM , Hojun CHOI , Kyungsun CHOI , Seung-Wook RYU
IPC分类号： A61K38/17 , A61K38/00 , A61K47/69 , C07K14/705 , C07K16/18 , C07K16/28 , C12N15/62 , C12N15/85 , C12P21/02
CPC分类号： A61K38/177 , A61K47/6917 , C07K14/705 , C07K14/70596 , C07K16/18 , C07K16/28 , C12N15/62 , C12N15/85 , C12P21/02 , A61K38/00 , C07K2317/80 , C07K2319/03 , C07K2319/70
摘要： The present invention provides a method for producing an exosome that transfers an active substance specifically to a target and the exosome produced by the same; a method for delivering the active substance to the target tissue using the exosome; a pharmaceutical composition for delivery of the active substance comprising the exosome as an active ingredient; and a composition for preparing the exosome comprising an expression vector wherein the target peptide is inserted into an extracellular portion of a transmembrane protein.
-
2.发明申请公开(公告)号：US20200206360A1
公开(公告)日：2020-07-02
申请号：US16639740
申请日：2018-08-16
发明人： Chulhee CHOI , Nambin YIM , Hojun CHOI , Kyungsun CHOI , Seung-Wook RYU
IPC分类号： A61K47/69 , C07K14/705 , C12N15/63
摘要： The present invention provides a method for producing an exosome that transfers an active substance specifically to a target and the exosome produced by the same; a method for delivering the active substance to the target tissue using the exosome; a pharmaceutical composition for delivery of the active substance comprising the exosome as an active ingredient; and a composition for preparing the exosome comprising an expression vector wherein the target peptide is inserted into an extracellular portion of a transmembrane protein.
-
3.发明申请公开(公告)号：US20200289614A1
公开(公告)日：2020-09-17
申请号：US16887029
申请日：2020-05-29
申请人： ILIAS BIOLOGICS INC.
发明人： Chulhee CHOI , Nambin YIM , Won Do HEO , Seung-Wook RYU , Hojun CHOI , Kyungsun CHOI
IPC分类号： A61K38/17 , C07K16/28 , C12P21/02 , C12N15/62 , C12N15/85 , A61K47/69 , C07K16/18 , C07K14/705
摘要： The present invention relates to a method for the mass-production of exosome comprising a cargo protein, a vector for preparing the exosome, exosome including a cargo protein prepared by the method, and a method for loading the cargo protein to cytosol by using the exosome prepared thereby. According to the method for preparing an exosome comprising a cargo protein provided by the present invention, the exosome loaded with a cargo protein can be produced with a high yield, so that it can be used broadly in the treatment of disease using the exosome.
-
-
搜索结果
3 条记录 (耗时 0.012 秒)
