公开(公告)号：US11534479B2

公开(公告)日：2022-12-27

申请号：US16965700

申请日：2019-02-18

申请人： ILTOO PHARMA ,  ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS ,  SORBONNE UNIVERSITÉ

发明人： David Klatzmann ,  Roberta Lorenzon ,  Michèle Rosenzwajg ,  Patrice Cacoub ,  Arsene Mekinian

IPC分类号： A61K38/20 ,  A61K47/68 ,  A61K47/60 ,  A61P37/00

摘要： The invention relates to the use of interleukin-2 in treating Sjögren's syndrome in a subject, wherein IL-2 is to be administered at a low dose of less than about 3.5 MIU/day.

公开(公告)号：US20190060407A1

公开(公告)日：2019-02-28

申请号：US15758800

申请日：2016-09-09

申请人： Assistance Publique - Hôpitaux De Paris ,  ILTOO PHARMA ,  SORBONNE UNIVERSITE

发明人： David Klatzmann ,  Francis Berenbaum ,  Jérémie Sellam ,  Bruno Fautrel ,  Roberta Lorenzon ,  Patrice Cacoub

IPC分类号： A61K38/20 ,  A61P19/02

摘要： The invention relates to the use of interleukin-2 in treating spondyloarthritis in a human subject, wherein IL-2 is to be administered at a dose of about I to about 2 MIU/day, wherein the treatment comprises at least a first course wherein interleukin-2 is administered once per day during at least 3 consecutive days, followed by a maintenance treatment after 1 to 4 weeks.