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公开(公告)号：US20200283519A1
公开(公告)日：2020-09-10
申请号：US16648886
申请日：2018-09-21
申请人： IMCHECK THERAPEUTICS SAS , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , INSTITUT JEAN PAOLI & IRENE CALMETTES , UNIVERSITÉ D'AIX-MARSEILLE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS
发明人： Daniel OLIVE , Christine PASERO
IPC分类号： C07K16/28
摘要： The present invention relates to antibodies having specificity for BTN2 and uses thereof, in particular for the treatment of cancer.
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公开(公告)号：US20220073619A1
公开(公告)日：2022-03-10
申请号：US17418017
申请日：2019-12-26
申请人： IMCHECK THERAPEUTICS SAS , INSTITUT JEAN PAOLI & IRENE CALMETTES , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS - , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , UNIVERSITÉ D'AIX-MARSEILLE
发明人： Alemseged TRUNEH , Christine PASERO , René HOET , Magali COLAZET , Daniel OLIVE
摘要： It is disclosed anti-BTN3A activating antibody fragments that specifically bind to BTN3A and activate the cytolytic function of Vγ9/Vδ2 T cells. The disclosure more specifically relates to specific anti-BTN3A binding proteins comprising such activating antibody fragments and their use in the manufacturing of novel drugs for use in treating cancer disorders, in particular cancers susceptible to be treated with activated γδ T cells.
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公开(公告)号：US20220162305A1
公开(公告)日：2022-05-26
申请号：US17440836
申请日：2020-03-20
申请人： IMCHECK THERAPEUTICS SAS , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - , INSTITUT JEAN PAOLI & IRENE CALMETTES , UNIVERSITÉ D'AIX-MARSEILLE
发明人： Etienne FOUCHER , Carla CANO , Kieu Suong LE , Christine PASERO , Daniel OLIVE
IPC分类号： C07K16/28
摘要： The present invention relates to antibodies having specificity for BTN2A and uses thereof, in particular for the treatment of cancer.
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4.发明申请公开(公告)号：US20160151489A1
公开(公告)日：2016-06-02
申请号：US14905842
申请日：2014-07-18
申请人： INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , ASSISTANCE PUBLIQUE HOPITAUX DE MARSEILLE , INSTITUT JEAN PAOLI & IRENE CALMETTES , UNIVERSITÉ D'AIX-MARSEILLE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
发明人： Daniel OLIVE , Christine PASERO
IPC分类号： A61K39/395 , A61K38/16 , C07K16/30
CPC分类号： A61K39/39558 , A61K38/168 , A61K38/177 , A61K38/1793 , A61K2039/505 , C07K16/2878 , C07K16/3069 , C07K2317/77 , A61K2300/00
摘要： The invention relates to i) a ligand of HVEM, and ii) an immunotoxin, as a combined preparation for simultaneous, separate or sequential use in the treatment of a solid tumor.
摘要翻译： 本发明涉及i）HVEM的配体，和ii）免疫毒素，作为在治疗实体瘤中同时，分开或顺序使用的组合制剂。
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公开(公告)号：US20240117041A1
公开(公告)日：2024-04-11
申请号：US18147331
申请日：2022-12-28
申请人： IMCHECK THERAPEUTICS SAS , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , INSTITUT JEAN PAOLI & IRENE CALMETTES , UNIVERSITÉ D'AIX-MARSEILLE , CENTRE NATIONAL DE LA RECHECHE SCIENTIFIQUE - CNRS
发明人： Daniel OLIVE , Christine PASERO
IPC分类号： C07K16/28
CPC分类号： C07K16/2803 , C07K2317/21 , C07K2317/24 , C07K2317/92
摘要： The present invention relates to antibodies having specificity for BTN2 and uses thereof, in particular for the treatment of cancer.
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公开(公告)号：US20220112289A1
公开(公告)日：2022-04-14
申请号：US17264507
申请日：2019-07-31
申请人： Imcheck Therapeutics SAS , INSERM (Institut National de La Santé et de la Recherche Médicale) , Université Aix Marseille , Institut Jean Paoili & Irene Calmette , Centre National de la Recherche Scientifique - CNRS
摘要： The present invention relates to humanized antibodies that specifically bind to human BTN3A and their use in treating cancer and infectious disorders.
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公开(公告)号：US20230322932A1
公开(公告)日：2023-10-12
申请号：US18327127
申请日：2023-06-01
申请人： Imcheck Therapeutics SAS , INSERM (Institut National de la Santé et de la Recherche Médicale) , Université Aix Marseille , Institut Jean Paoili & Irene Calmette , Centre National de la Recherche Scientifique - CNRS
IPC分类号： C07K16/28 , A61K38/20 , A61P35/00 , A61K9/19 , A61K39/395
CPC分类号： C07K16/2827 , A61K38/2013 , A61P35/00 , A61K9/19 , A61K39/3955 , C07K16/2818 , A61K38/2086 , A61K2039/507
摘要： The present invention relates to humanized antibodies that specifically bind to human BTN3A and their use in treating cancer and infectious disorders.
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公开(公告)号：US20230272080A1
公开(公告)日：2023-08-31
申请号：US17935154
申请日：2022-09-26
申请人： Imcheck Therapeutics SAS , NSERM (Institut National de la Santé et de Recherche Médicale) , Université Aix Marseille , Institut Jean Paoili & Irene Calmette , Centre National de la Recherche Scientifique - CNRS
IPC分类号： C07K16/28 , A61P35/00 , A61K9/19 , A61K38/20 , A61K39/395
CPC分类号： C07K16/2827 , A61P35/00 , A61K9/19 , A61K38/2013 , A61K38/2086 , A61K39/3955 , C07K16/2818 , A61K39/00
摘要： The present invention relates to humanized antibodies that specifically bind to human BTN3A and their use in treating cancer and infectious disorders.
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