专利检索 ap:("IMCHECK THERAPEUTICS SAS" OR "INSTITUT JEAN PAOLI & IRENE CALMETTES" OR "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS -" OR "INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)" OR "UNIVERSITÉ D'AIX-MARSEILLE") AND inv:"René HOET" 第 1 页

1.

发明申请
BTN3A BINDING PROTEINS AND USES THEREOF 有权

公开(公告)号：US20220073619A1

公开(公告)日：2022-03-10

申请号：US17418017

申请日：2019-12-26

申请人： IMCHECK THERAPEUTICS SAS , INSTITUT JEAN PAOLI & IRENE CALMETTES , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS - , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , UNIVERSITÉ D'AIX-MARSEILLE

发明人： Alemseged TRUNEH , Christine PASERO , René HOET , Magali COLAZET , Daniel OLIVE

IPC分类号： C07K16/28 , C12N15/63

摘要： It is disclosed anti-BTN3A activating antibody fragments that specifically bind to BTN3A and activate the cytolytic function of Vγ9/Vδ2 T cells. The disclosure more specifically relates to specific anti-BTN3A binding proteins comprising such activating antibody fragments and their use in the manufacturing of novel drugs for use in treating cancer disorders, in particular cancers susceptible to be treated with activated γδ T cells.