公开(公告)号：US20210364409A1

公开(公告)日：2021-11-25

申请号：US16957101

申请日：2018-12-19

Applicant: IMEC VZW

Inventor： Chengxun LIU ,  Dries VERCRUYSSE ,  Niels VERELLEN ,  Abdulkadir YURT

IPC: G01N15/14

Abstract: A device (110) for illuminating a particle comprises: a light waveguide (112; 412a, 412b; 512a, 512b) arranged on a substrate (114); an output coupler (118) configured to output a light beam (150; 450a, 450b; 550a, 550b) forming a sheet-like shape having a cross-section which has an extension in a first direction being larger than a size of a particle; and a fluidic channel (116; 416; 516) arranged on the substrate (114) for guiding a flow of particles along a longitudinal direction of the fluidic channel (116; 416; 516); wherein the sheet-like shape of the light beam (150; 450a, 450b; 550a, 550b) is arranged within the fluidic channel (116; 416; 516) and the first direction of the cross-section of the light beam (150; 450a, 450b; 550a, 550b) forms an angle to the longitudinal direction of the fluidic channel (116; 416; 516). A system (100) for imaging the particle comprises the device, an array (130; 430a, 430b; 530) of light-detecting elements (132; 432a, 432b; 532); and a lens (120) to converge light towards the array (130; 430a, 430b; 530) such that each light-detecting element (132; 432a, 432b; 532) detects light originating from a corresponding position in the fluidic channel (116; 416; 516).

公开(公告)号：US20200018684A1

公开(公告)日：2020-01-16

申请号：US16335578

申请日：2017-09-18

Applicant: IMEC VZW

Inventor： Dries VERCRUYSSE

IPC: G01N15/14 ,  G01N21/47

Abstract: An optical excitation system comprises a substrate (105) comprising at least one delivery means (104), for delivering analytes (109) into at least one region of interest (103), at least one radiation carrier (101) for directing at least one radiation beam from the at least one radiation carrier (101) into the at least one region of interest (103). The substrate (105) includes a thin lens system (120) comprising at least a first thin lens (121), for collimating radiation from the at least one region of interest (103) to a remote detection system (130). A particle sensor and sensing system comprising the excitation system are also provided, for example a modular particle sensor and modular sensing system, wherein the optical excitation system may be single use and disposable.