公开(公告)号：US20240116998A1

公开(公告)日：2024-04-11

申请号：US18264157

申请日：2022-02-15

Applicant: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION

Inventor： Richard D. DIMARCHI ,  Piotr Andrzej MROZ ,  Kishore THALLURI

IPC: C07K14/605 ,  A61P3/08

CPC classification number: C07K14/605 ,  A61P3/08 ,  A61K38/00

Abstract: Provided herein are GLP-1 receptor antagonists peptides and pharmaceutical compositions for the treatment of hypoglycemia. Further provided herein are methods of treating atypical hypoglycemia in patients that have become hyperinsulinemic, including those who become hyperinsulinemic after bariatric surgery.

公开(公告)号：US20240058422A1

公开(公告)日：2024-02-22

申请号：US18365081

申请日：2023-08-03

Applicant: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION

Inventor： Richard D. DiMARCHI ,  Piotr Andrzej MROZ ,  Kishore THALLURI

IPC: A61K38/26

CPC classification number: A61K38/26

Abstract: Provided herein are GLP-1 receptor antagonists peptides and pharmaceutical compositions for the treatment of hypoglycemia. Further provided herein are methods of treating atypical hypoglycemia in patients that have become hyperinsulinemic, including those who become hyperinsulinemic after bariatric surgery.