公开(公告)号：US09649350B2

公开(公告)日：2017-05-16

申请号：US14556055

申请日：2014-11-28

Applicant: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY

Inventor： Cheol-Hee Choi ,  Hoon Cho ,  Young-Sook Moon ,  Ji-Won Han ,  Ju-Hee Han

IPC: A61K36/25 ,  A23L33/105

CPC classification number: A61K36/25 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/30 ,  A23V2200/3202 ,  A23V2250/21

Abstract: Provided is a 15-PGDH activity adjusting function of a Dendropanax morbifera extract. More specifically, since it has been confirmed that the Dendropanax morbifera extract has an outstanding effect in suppressing 15-PGDH activity and so increasing PGE2, a composition of the present invention which contains the Dendropanax morbifera extract as an active ingredient has the advantage of being able to be used for producing a functional health food and a therapeutic agent for a disease associated with PGE2.

公开(公告)号：US20150202241A1

公开(公告)日：2015-07-23

申请号：US14556055

申请日：2014-11-28

Applicant: Industry-Academic Cooperation Foundation, Chosun University

Inventor： Cheol-Hee CHOI ,  Hoon Cho ,  Young-Sook Moon ,  Ji-Won Han ,  Ju-Hee Han

IPC: A61K36/25 ,  A23L1/30

CPC classification number: A61K36/25 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/30 ,  A23V2200/3202 ,  A23V2250/21

Abstract: Provided is a 15-PGDH activity adjusting function of a Dendropanax morbifera extract. More specifically, since it has been confirmed that the Dendropanax morbifera extract has an outstanding effect in suppressing 15-PGDH activity and so increasing PGE2, a composition of the present invention which contains the Dendropanax morbifera extract as an active ingredient has the advantage of being able to be used for producing a functional health food and a therapeutic agent for a disease associated with PGE2.

Abstract translation: 提供了Dendropanax morbifera提取物的15-PGDH活性调节功能。 更具体地说，由于已确认了Dendropanax morbifera提取物在抑制15-PGDH活性和PGE2增加方面具有突出的效果，因此含有Dendropanax morbifera提取物作为活性成分的本发明的组合物具有能够 用于制备功能性保健食品和与PGE2相关的疾病的治疗剂。

公开(公告)号：US10787425B2

公开(公告)日：2020-09-29

申请号：US16068518

申请日：2016-08-18

Applicant: INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY

Inventor： Hoon Cho ,  Eunjeong Yoon

IPC: C07D277/34 ,  C07D277/36 ,  A61P9/10 ,  A61P17/14 ,  A61P9/12 ,  A61P13/12 ,  A61P17/02 ,  A61P9/04 ,  A61P1/04

Abstract: Provided are a novel compound represented by any one of Formulae 1a and 1b and use thereof. Provided are novel thiazolidinedione derivatives represented by any one of Formulae 1a and 1b and pharmaceutical compositions containing the same.