公开(公告)号：US20140308723A1

公开(公告)日：2014-10-16

申请号：US14176094

申请日：2014-02-09

Applicant: INEOS BIO SA

Inventor： Peter Simpson BELL ,  Song LIU

IPC: C12P7/06 ,  C12P3/00

CPC classification number: C12P7/06 ,  C12P3/00 ,  C12P7/065 ,  Y02E50/17

Abstract: A process provides high ethanol productivity levels during fermentation of a CO-containing substrate. The process controls CO-substrate feed rates and cell density to avoid culture upset and CO inhibition. The process includes fermenting a CO-containing gaseous substrate to obtain a target cell density and a target CO feed rate, and then periodically reducing and increasing the CO feed rate.

Abstract translation: 一种方法在含CO底物的发酵过程中提供高的乙醇生产率水平。 该过程控制CO底物进料速率和细胞密度，以避免培养不适和CO抑制。 该方法包括发酵含CO气体底物以获得目标细胞密度和目标CO进料速率，然后周期性地降低和提高CO进料速率。