公开(公告)号：US12059563B2

公开(公告)日：2024-08-13

申请号：US17981174

申请日：2022-11-04

申请人： INMODE LTD

发明人： Deborah Wilkerson ,  Stacie Bell ,  Bruce Baldwin Allan

IPC分类号： A61N1/36 ,  A61N1/02 ,  A61N1/40 ,  A61N5/02 ,  A61N5/04 ,  A61N7/02 ,  A61N1/05 ,  A61N7/00

CPC分类号： A61N1/36007 ,  A61N1/025 ,  A61N1/403 ,  A61N5/025 ,  A61N5/045 ,  A61N7/022 ,  A61N1/0524 ,  A61N2007/0004

摘要： Methods for treating urinary stress incontinence by non-invasively delivering energy to one or more submucosal regions of vaginal tissue to induce remodeling within the vaginal tissue are provided. In some embodiments, the energy delivery results in heating of the target tissue to a temperature that ranges from about 38° C. to about 46° C. In some embodiments, the subject methods involve cooling a mucosal epithelial layer over the vaginal tissue. In some embodiments, a reverse thermal gradient is produced as the mucosal epithelium is cooled while energy is delivered to the underlying vaginal tissue.