公开(公告)号：US20190127463A1

公开(公告)日：2019-05-02

申请号：US16240906

申请日：2019-01-07

Applicant: INNATE PHARMA

Inventor： CECILE BONNAFOUS ,  HELENE SICARD ,  RENAUD BUFFET

IPC: C07K16/28 ,  C07K16/30 ,  G01N33/574

Abstract: The present invention relates to methods for the treatment, prevention and diagnosis of peripheral T cell lymphoma using compounds that specifically bind KIR3DL2. The invention also relates to use of antibodies that specifically bind KIR3DL2 in diagnostic and theranostic assays in the detection and treatment of peripheral T cell lymphoma.

公开(公告)号：US20180369373A1

公开(公告)日：2018-12-27

申请号：US15747190

申请日：2016-07-04

Applicant: INNATE PHARMA

Inventor： NADIA ANCERIZ ,  CECILE BONNAFOUS ,  ARNAUD DUJARDIN ,  CARINE PATUREL

IPC: A61K39/395 ,  C07K16/28 ,  A61P35/00 ,  G01N33/566 ,  G01N33/574

Abstract: The present invention relates to methods for detecting and monitoring NK cells in paraffin-embedded tissue samples. Also provided are antibodies, antibody fragments, and derivatives thereof that specifically bind to NKp46 present on the surface of NK cells in paraffin-embedded tissue samples.

公开(公告)号：US20170298132A1

公开(公告)日：2017-10-19

申请号：US15623572

申请日：2017-06-15

Applicant: INNATE PHARMA

Inventor： CECILE BONNAFOUS ,  HELENE SICARD ,  RENAUD BUFFET

IPC: C07K16/28 ,  G01N33/574 ,  C07K16/30 ,  A61K39/00

CPC classification number: C07K16/2803 ,  A61K2039/505 ,  C07K16/3023 ,  C07K16/3061 ,  C07K2317/33 ,  C07K2317/34 ,  C07K2317/732 ,  G01N33/57426 ,  G01N2333/705 ,  G01N2333/70503

Abstract: The present invention relates to methods for the treatment, prevention and diagnosis of peripheral T cell lymphoma using compounds that specifically bind KIR3DL2. The invention also relates to use of antibodies that specifically bind KIR3DL2 in diagnostic and theranostic assays in the detection and treatment of peripheral T cell lymphoma.