公开(公告)号：US10968281B2

公开(公告)日：2021-04-06

申请号：US16341529

申请日：2017-10-13

申请人： INSTITUT CURIE ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

发明人： Elodie Segura ,  Sebastian Amigorena ,  Franck Perez ,  Sandrine Moutel

IPC分类号： A61K39/395 ,  A61K39/00 ,  G01N33/53 ,  C07K16/46 ,  C07K16/00 ,  C07K16/30 ,  G01N33/50 ,  A61K38/00

摘要： The present invention provides a new anti-LSP1 (Leukocyte specific protein 1) antibody. This new antibody allows the specific staining of inflammatory dendritic cells and can be used in diagnosis methods or as a medicament when conjugated to a drug.

公开(公告)号：US20210060158A1

公开(公告)日：2021-03-04

申请号：US16644159

申请日：2018-09-19

申请人： INSTITUT CURIE ,  INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

发明人： Sebastian Amigorena ,  Elodie Segura

IPC分类号： A61K39/395 ,  A61K31/404 ,  A61K31/407 ,  A61K31/352 ,  A61K31/353 ,  A61K31/7048 ,  A61K31/4439 ,  A61K31/47 ,  A61K31/42 ,  A61K31/505 ,  A61K31/4184 ,  A61K31/198 ,  A61K38/17 ,  A61K38/44 ,  A61P35/00

摘要： The present invention relates to an AhR agonist for use in combination with at least one immune checkpoint modulator in the treatment of cancer. The present invention also encompasses product containing an AhR agonist and at least one immune checkpoint modulator as defined in any one of the preceding, claims, as a combined preparation for simultaneous, separate or sequential use in the treatment of cancer.