专利检索 ap:("INSTITUT CURIE" OR "INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)" OR "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE" OR "PARIS SCIENCES ET LETTRES") AND inv:"SEBASTIAN MÜLLER" 第 1 页

1.

发明公开
DIMER OF BIGUANIDINES AND THEIR THERAPEUTIC USES 审中-公开

公开(公告)号：US20230416196A1

公开(公告)日：2023-12-28

申请号：US18037331

申请日：2021-11-18

申请人： INSTITUT CURIE , INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , PARIS SCIENCES ET LETTRES

发明人： RAPHAËL RODRIGUEZ , ANTOINE VERSINI , TATIANA CAÑEQUE , SEBASTIAN MÜLLER , STÉPHANIE SOLIER , LEEROY BARON

IPC分类号： C07C279/26 , A61P35/00

CPC分类号： C07C279/265 , A61P35/00

摘要： The present invention relates to compounds comprising two biguanidyl radicals that can be useful as anti-inflammatory agent, and also to new compounds comprising two biguanidyl radicals and their use as a drug, in particular for treating a cancer, a metabolic disease, a secondary mitochondrial disorder due to copper overload including Indian childhood cirrhosis, Wilson's disease and Idiopathic infantile copper toxicosis or due to iron overload, an infection by a virus such as a coronavirus or an influenza virus, a neurodegenerative disease or disorder and aging.