公开(公告)号：US20160017338A1

公开(公告)日：2016-01-21

申请号：US14849777

申请日：2015-09-10

Applicant: INTERNA TECHNOLOGIES B.V.

Inventor： Roeland Quirinus Jozef SCHAAPVELD ,  Gerardus Wilhelmus Christiaan Theodoor VERHAEGH ,  Jacobus Antonius SCHALKEN ,  Andreas Alphons Franciscus Ludovicus van PUIJENBROEK ,  Willemijn Maria GOMMANS ,  Sanne WEIJZEN

IPC: C12N15/113 ,  A61K45/06 ,  A61N5/10 ,  A61K31/713

CPC classification number: C12N15/1138 ,  A61K31/7088 ,  A61K31/7105 ,  A61K31/713 ,  A61K45/06 ,  A61N5/10 ,  C12N15/113 ,  C12N2310/141 ,  C12N2320/31 ,  C12N2330/10

Abstract: The invention relates to the diagnostic and therapeutic uses of a miRNA molecule or an equivalent thereof wherein a source of said miRNA molecule or equivalent thereof comprises at least 80 nucleotides and comprises a motif having at least 98% identity with the motif represented by SEQ ID NO:1 or a source thereof in a disease and condition associated with EMT (Epithelial to Mesenchymal Transition).