公开(公告)号：US07358231B1

公开(公告)日：2008-04-15

申请号：US11606949

申请日：2006-12-01

申请人： Ian McCaffey ,  Kim Alving ,  Bruno Domon ,  Steven Ruben

发明人： Ian McCaffey ,  Kim Alving ,  Bruno Domon ,  Steven Ruben

IPC分类号： A61K31/00 ,  C07K1/00

CPC分类号： C07K14/4748 ,  G01N33/57438

摘要： The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAST) and antibodies binds to PCAST. The present invention provides that PCAST is used as targets for screening agents that modulates the PCAST activities. Further the present invention provides methods for treating diseases associated with pancreas.

摘要翻译： 本发明提供了诊断和检测与胰腺相关疾病的方法。 本发明提供在胰腺疾病（PCAST​​）中差异表达的一种或多种蛋白质或其片段，肽或核酸分子，并且抗体结合PCAST​​。 本发明提供PCAST​​作为调节PCAST​​活性的筛选试剂的靶标。 此外，本发明提供了治疗与胰腺相关疾病的方法。