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公开(公告)号:US20220402880A1
公开(公告)日:2022-12-22
申请号:US17753980
申请日:2020-09-23
发明人: Nilesh ZAWARE , Ming-Ming ZHOU , Chunyan REN , Claudia KIM , Sudeh IZADMEHR , Matthew GALSKY
IPC分类号: C07D235/30 , C07D209/08 , C07D403/06 , A61P35/00
摘要: A genus of bicyclic inhibitors of CBX chromodomains is disclosed. The compounds are of the following genus: The compounds inhibit CBX proteins and, as a consequence, they are useful for treating prostate cancer, ovarian cancer, and B-cell lymphoma.