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公开(公告)号:US09150517B2
公开(公告)日:2015-10-06
申请号:US14699965
申请日:2015-04-29
申请人: Ignyta, Inc.
发明人: Roger P. Bakale , Peter D. Brown , Jian Chen , Anthony S. Drager , Rachel Y. Labell , Robert E. McKean , Piyush R. Patel , Renee C. Roemmele
IPC分类号: C07D235/16
CPC分类号: A61K31/4184 , A61K9/14 , A61K47/42 , C07D235/16
摘要: The present invention is directed to bendamustine esters and bendamustine amides and their use for the treatment of cancer.
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公开(公告)号:US09452988B2
公开(公告)日:2016-09-27
申请号:US14442088
申请日:2013-11-12
申请人: Ignyta, Inc.
发明人: Roger P. Bakale , Peter D. Brown , Jian Chen , Anthony S. Drager , Rachel Y. Labell , Robert E. McKean , Piyush R. Patel , Renee C. Roemmele , Bradley McIntyre
IPC分类号: C07D235/16 , A61K9/14 , A61K31/4184 , A61K47/42
CPC分类号: A61K31/4184 , A61K9/14 , A61K47/42 , C07D235/16
摘要: The present invention is directed to bendamustine esters and bendamustine amides and their use for the treatment of cancer.
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公开(公告)号:US20170182008A1
公开(公告)日:2017-06-29
申请号:US15456439
申请日:2017-03-10
申请人: IGNYTA, INC.
发明人: Roger P. Bakale , Peter D. Brown , Jian Chen , Anthony S. Drager , Rachel Y. LaBell , Robert E. McKean , Piyush R. Patel , Renee C. Roemmele
IPC分类号: A61K31/4184 , A61K9/14 , A61K47/42
CPC分类号: A61K31/4184 , A61K9/14 , A61K47/42 , C07D235/16
摘要: The present invention is directed to bendamustine esters and bendamustine amides and their use for the treatment of cancer.
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公开(公告)号:US09149464B2
公开(公告)日:2015-10-06
申请号:US14711747
申请日:2015-05-13
申请人: Ignyta, Inc.
发明人: Roger P. Bakale , Peter D. Brown , Jian Chen , Anthony S. Drager , Rachel Y. Labell , Robert E. McKean , Piyush R. Patel , Renee C. Roemmele
IPC分类号: C07D235/16 , A61K31/4184 , A61K47/42 , A61K9/14
CPC分类号: A61K31/4184 , A61K9/14 , A61K47/42 , C07D235/16
摘要: The present invention is directed to bendamustine esters and bendamustine amides and their use for the treatment of cancer.
摘要翻译: 本发明涉及苯达莫司汀酯和苯达莫司汀酰胺及其用于治疗癌症的用途。
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公开(公告)号:US09913827B2
公开(公告)日:2018-03-13
申请号:US15456439
申请日:2017-03-10
申请人: IGNYTA, INC.
发明人: Roger P. Bakale , Peter D. Brown , Jian Chen , Anthony S. Drager , Rachel Y. LaBell , Robert E. McKean , Piyush R. Patel , Renee C. Roemmele
IPC分类号: A61K31/4184 , C07D235/16 , A61K47/42 , A61K9/14
CPC分类号: A61K31/4184 , A61K9/14 , A61K47/42 , C07D235/16
摘要: The present invention is directed to bendamustine esters and bendamustine amides and their use for the treatment of cancer.
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公开(公告)号:US09630926B2
公开(公告)日:2017-04-25
申请号:US15184968
申请日:2016-06-16
申请人: Ignyta, Inc.
发明人: Roger P. Bakale , Peter D. Brown , Jian Chen , Anthony S. Drager , Rachel Y. LaBell , Robert E. McKean , Piyush R. Patel , Renee C. Roemmele
IPC分类号: C07D235/16 , A61K9/14 , A61K31/4184 , A61K47/42
CPC分类号: A61K31/4184 , A61K9/14 , A61K47/42 , C07D235/16
摘要: The present invention is directed to bendamustine esters and bendamustine amides and their use for the treatment of cancer.
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公开(公告)号:US20150274675A1
公开(公告)日:2015-10-01
申请号:US14442088
申请日:2013-11-12
申请人: Ignyta, Inc.
发明人: Roger P. Bakale , Peter D. Brown , Jian Chen , Anthony S. Drager , Rachel Y. Labell , Robert E. McKean , Piyush R. Patel , Renee C. Roemmele
IPC分类号: C07D235/16
CPC分类号: A61K31/4184 , A61K9/14 , A61K47/42 , C07D235/16
摘要: The present invention is directed to bendamustine esters and bendamustine amides and their use for the treatment of cancer.
摘要翻译: 本发明涉及苯达莫司汀酯和苯达莫司汀酰胺及其用于治疗癌症的用途。
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