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公开(公告)号:US20200222398A1
公开(公告)日:2020-07-16
申请号:US16716574
申请日:2019-12-17
Inventor: Jian-Ting Zhang , Liu Jing-Yuan
IPC: A61K31/4985 , A61P35/00
Abstract: Methods for treating various cancers by administering one or more compounds that target the dimeric protein survivin are disclosed. Pharmaceutical compositions containing such compounds are also disclosed, along with general methods of identifying anti-cancer compounds that target oncogenic dimeric proteins. Exemplary compounds that can be used in the disclosed methods of treatment and pharmaceutical compositions have the chemical structure: