公开(公告)号：US11252965B2

公开(公告)日：2022-02-22

申请号：US16316847

申请日：2017-07-13

Applicant: Indiana University Research and Technology Corporation ,  University of Notre Dame du Lac

Inventor： Molly Duman Scheel ,  David W. Severson ,  Kathleen Eggleson ,  Na Wei

IPC: C12N15/113 ,  C12N15/81 ,  A01N57/16 ,  A01K67/033 ,  A01N25/00 ,  A01N25/02 ,  A01N25/10 ,  A01N63/60

Abstract: The present invention provides a novel class of insecticides for control of disease vector insects, particularly mosquitoes. These insecticides prevent maturation or development of larvae into adult insects using interfering RNA (iRNA). The present invention further includes compositions comprising iRNA and methods of controlling, reducing, or treating an insect infestation with the iRNA or compositions described herein.

公开(公告)号：US20220346380A1

公开(公告)日：2022-11-03

申请号：US17571193

申请日：2022-01-07

Applicant: Indiana University Research and Technology Corporation ,  University of Notre Dame du Lac

Inventor： Molly Duman Scheel ,  David W. Severson ,  Kathleen Eggleson ,  Na Wei

IPC: A01N57/16 ,  A01K67/033 ,  A01N25/00 ,  A01N25/02 ,  A01N25/10 ,  C12N15/113 ,  C12N15/81 ,  A01N63/60

Abstract: The present invention provides a novel class of insecticides for control of disease vector insects, particularly mosquitoes. These insecticides prevent maturation or development of larvae into adult insects using interfering RNA (iRNA). The present invention further includes compositions comprising iRNA and methods of controlling, reducing, or treating an insect infestation with the iRNA or compositions described herein.

公开(公告)号：US20190297879A1

公开(公告)日：2019-10-03

申请号：US16316847

申请日：2017-07-13

Applicant: Indiana University Research and Technology Corporation ,  University of Notre Dame du Lac

Inventor： Molly Duman Scheel ,  David W. Severson ,  Kathleen Eggleson ,  Na Wei

IPC: A01N25/00 ,  A01K67/033 ,  C12N15/81 ,  C12N15/113 ,  A01N25/02 ,  A01N25/10 ,  A01N63/04

Abstract: The present invention provides a novel class of insecticides for control of disease vector insects, particularly mosquitoes. These insecticides prevent maturation or development of larvae into adult insects using interfering RNA (iRNA). The present invention further includes compositions comprising iRNA and methods of controlling, reducing, or treating an insect infestation with the iRNA or compositions described herein.

公开(公告)号：US20220248690A1

公开(公告)日：2022-08-11

申请号：US17288748

申请日：2019-10-26

Applicant: Indiana University Research and Technology Corporation

Inventor： Molly Duman Scheel

IPC: A01N63/60 ,  C12N15/113

Abstract: The present disclosure provides insecticides that can specifically target mosquitoes based on their sex. These sex-specific insecticides prevent maturation or development of larvae into adult insects using interfering RNA (iRNA). The present disclosure further provides compositions comprising sex-linked iRNA and methods of controlling, reducing, or treating an insect infestation with the iRNA or compositions described herein. The compositions and methods described herein can be used to sort mosquitoes based on sex.