公开(公告)号：US08562953B2

公开(公告)日：2013-10-22

申请号：US13633485

申请日：2012-10-02

Applicant: Industrial Technology Research Institute

Inventor： Dhakshanamurthy Thirumalai ,  Chin-I Lin ,  Shian-Jy Wang

IPC: C08L73/00 ,  A61K9/00 ,  C07D407/00

CPC classification number: C08G83/003 ,  A61K49/124

Abstract: A dendritic polymer and a magnetic resonance imaging contrast agent employing the same. The magnetic resonance contrast agent includes the dendritic polymer according to the structure of SP-DZ-L)i)j or SP-DX-Z-L)i)j, wherein, S is cyclosilane moiety with j silicon oxygen residual groups, and j is not less than 2; P is CH2CH2Ol, and l is not less than 1; D is a C3-30 dendritic moiety having n oxygen residue, and n is not less than 3; X is C3-30 moiety having bi-functional groups; Z is a C3-20 moiety having a plurality of functional group; and L is a metal cation.

Abstract translation: 树突状聚合物和使用其的磁共振成像造影剂。 磁共振造影剂包括根据SP-DZ-L）i）j或SP-DX-ZL）i）j的结构的树枝状聚合物，其中S是具有j个硅氧残基的环硅烷部分，j是 不低于2; P是CH 2 CH 2 O，l不小于1; D是具有n个氧残基的C3-30树枝状部分，n不小于3; X是具有双官能团的C3-30部分; Z是具有多个官能团的C3-20部分; L是金属阳离子。