公开(公告)号：US20190331631A1

公开(公告)日：2019-10-31

申请号：US16398273

申请日：2019-04-30

Applicant: Industrial Technology Research Institute

Inventor： Hui-Chu Hsieh ,  Wen-Pin Hsieh ,  Nien-Jen Chou ,  Hui-Ju Shen ,  Hui-Ling Peng ,  Jing-Tsyr Lin

IPC: G01N27/327 ,  G01N33/543 ,  C12Q1/00

Abstract: A biosensor and a biological detection method are provided. The biosensor includes a substrate, a plurality of first and second electrodes in a strip shape, a material layer and a capture antibody. The substrate has a sampling region and a measuring region connected to the sampling region. The first and second electrodes are disposed on the substrate in the measuring region, and the first and second electrodes are arranged alternately with each other, wherein the first electrodes are connected in parallel with each other, and the second electrodes are connected in parallel with each other. The material layer is disposed on the substrate in the measuring region and covers the first and second electrodes, wherein the material layer has a channel exposing a portion of each of the first electrodes and a portion of each of the second electrodes, the channel is connected to the sampling region, and an extending direction of the channel is interlaced with an extending direction of the first electrodes and the second electrodes. The capture antibody is disposed on the first and second electrodes exposed by the channel.

公开(公告)号：US11131644B2

公开(公告)日：2021-09-28

申请号：US16398273

申请日：2019-04-30

Applicant: Industrial Technology Research Institute

Inventor： Hui-Chu Hsieh ,  Wen-Pin Hsieh ,  Nien-Jen Chou ,  Hui-Ju Shen ,  Hui-Ling Peng ,  Jing-Tsyr Lin

IPC: G01N27/327 ,  C12Q1/00 ,  G01N33/543

Abstract: A biosensor and a biological detection method are provided. The biosensor includes a substrate, a plurality of first and second electrodes in a strip shape, a material layer and a capture antibody. The substrate has a sampling region and a measuring region connected to the sampling region. The first and second electrodes are disposed on the substrate in the measuring region, and the first and second electrodes are arranged alternately with each other, wherein the first electrodes are connected in parallel with each other, and the second electrodes are connected in parallel with each other. The material layer is disposed on the substrate in the measuring region and covers the first and second electrodes, wherein the material layer has a channel exposing a portion of each of the first electrodes and a portion of each of the second electrodes, the channel is connected to the sampling region, and an extending direction of the channel is interlaced with an extending direction of the first electrodes and the second electrodes. The capture antibody is disposed on the first and second electrodes exposed by the channel.