专利检索 ap:("Infinity Pharmaceuticals, Inc.") AND inv:"Jason Kropp" 第 1 页

1.

发明申请
PROCESSES FOR PREPARING ISOQUINOLINONES AND SOLID FORMS OF ISOQUINOLINONES 审中-公开

公开(公告)号：US20180273535A1

公开(公告)日：2018-09-27

申请号：US15799612

申请日：2017-10-31

申请人： Infinity Pharmaceuticals, Inc.

发明人： Pingda Ren , Michael Martin , Paul Isbester , Benjamin S. Lane , Jason Kropp

IPC分类号： C07D473/34

摘要： Polymorphs of chemical compounds that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including Pl3 kinase activity, are described herein. Also provided herein are processes for preparing compounds, polymorphs thereof, and pharmaceutical compositions thereof.

2.

发明授权
Processes for preparing isoquinolinones and solid forms of isoquinolinones 有权
标题翻译：制备异喹啉酮和固体形式异喹啉酮的方法

公开(公告)号：US09290497B2

公开(公告)日：2016-03-22

申请号：US14327499

申请日：2014-07-09

申请人： INFINITY PHARMACEUTICALS, INC.

发明人： Pingda Ren , Michael Martin , Paul Isbester , Benjamin S. Lane , Jason Kropp

IPC分类号： C07D473/34 , A61K31/52 , A61P35/00

CPC分类号： C07D473/34

摘要： Polymorphs of chemical compounds that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including P13 kinase activity, are described herein. Also provided herein are processes for preparing compounds, polymorphs thereof, and pharmaceutical compositions thereof.

摘要翻译： 本文描述了调节激酶活性的化合物的多晶型物质，包括PI3激酶活性，以及化合物，药物组合物和治疗与激酶活性（包括P13激酶活性）相关的疾病和病症的方法。本文还提供了制备化合物，多晶型物及其药物组合物的方法。

3.

发明授权
Solid forms of (S)-3-(1-(9H-purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one and methods of use thereof 有权

公开(公告)号：US10550122B2

公开(公告)日：2020-02-04

申请号：US15799612

申请日：2017-10-31

申请人： Infinity Pharmaceuticals, Inc.

发明人： Pingda Ren , Michael Martin , Paul Isbester , Benjamin S. Lane , Jason Kropp

IPC分类号： C07D473/34 , A61K31/52 , A61P35/00 , A61P37/00 , A61P11/06

摘要： Polymorphs of chemical compounds that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including Pl3 kinase activity, are described herein. Also provided herein are processes for preparing compounds, polymorphs thereof, and pharmaceutical compositions thereof.

4.

再颁专利
Processes for preparing isoquinolinones and solid forms of isoquinolinones 有权

公开(公告)号：USRE46621E1

公开(公告)日：2017-12-05

申请号：US15051529

申请日：2016-02-23

申请人： Infinity Pharmaceuticals, Inc.

发明人： Pingda Ren , Michael Martin , Paul Isbester , Benjamin S. Lane , Jason Kropp

IPC分类号： C07D473/34 , A61P35/00 , A61K31/52

CPC分类号： C07D473/34

摘要： Polymorphs of chemical compounds that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including P13 kinase activity, are described herein. Also provided herein are processes for preparing compounds, polymorphs thereof, and pharmaceutical compositions thereof.

5.

发明授权
Formulations of (S)-3-(1-(9H-purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one 有权

公开(公告)号：US11312718B2

公开(公告)日：2022-04-26

申请号：US16734135

申请日：2020-01-03

申请人： Infinity Pharmaceuticals, Inc.

发明人： Pingda Ren , Michael Martin , Paul Isbester , Benjamin S. Lane , Jason Kropp

IPC分类号： C07D473/34 , A61K31/52 , A61P35/00 , A61P37/00 , A61P11/06 , A61P29/00

摘要： Polymorphs of chemical compounds that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including P13 kinase activity, are described herein. Also provided herein are processes for preparing compounds, polymorphs thereof, and pharmaceutical compositions thereof.

6.

发明授权
Solid forms of (S)-3-(1-(9H-purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1 (2H)-one and methods of use thereof 有权

公开(公告)号：US09840505B2

公开(公告)日：2017-12-12

申请号：US15016117

申请日：2016-02-04

申请人： Infinity Pharmaceuticals, Inc.

发明人： Pingda Ren , Michael Martin , Paul Isbester , Benjamin S. Lane , Jason Kropp

IPC分类号： C07D473/34 , A61K31/52 , A61P35/00

CPC分类号： C07D473/34

摘要： Polymorphs of chemical compounds that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. Also provided herein are processes for preparing compounds, polymorphs thereof, and pharmaceutical compositions thereof.