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1.发明授权公开(公告)号：US11976126B2
公开(公告)日：2024-05-07
申请号：US17394900
申请日：2021-08-05
申请人： Inhibrx, Inc.
发明人： John C. Timmer , Kyle S. Jones , Amir S. Razai , Abrahim Hussain , Katelyn M. Willis , Quinn Deveraux , Brendan P. Eckelman
IPC分类号： A61K39/395 , C07K16/28 , A61K39/00
CPC分类号： C07K16/2878 , A61K39/39558 , A61K2039/505 , C07K2317/22 , C07K2317/24 , C07K2317/33 , C07K2317/35 , C07K2317/567 , C07K2317/569 , C07K2317/73 , C07K2317/75
摘要： The disclosure relates generally to molecules that specifically engage death receptor 5 (DR5), a member of the TNF receptor superfamily (TNFRSF). More specifically the disclosure relates to multivalent and multispecific molecules that bind at least DR5.
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公开(公告)号：US11117972B2
公开(公告)日：2021-09-14
申请号：US16295332
申请日：2019-03-07
申请人： Inhibrx, Inc.
发明人： Brendan P. Eckelman , John C. Timmer , Chelsie Hata , Kyle S. Jones , Abrahim Hussain , Amir S. Razai , Bryan Becklund , Rajay Pandit , Mike Kaplan , Lucas Rascon , Quinn Deveraux
摘要： This invention relates generally to molecules that specifically engage OX40, a member of the TNF receptor superfamily (TNFRSF). More specifically this invention relates to multivalent and multispecific molecules that bind at least OX40.
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公开(公告)号：US11566078B2
公开(公告)日：2023-01-31
申请号：US16601825
申请日：2019-10-15
申请人： Inhibrx, Inc.
发明人： Brendan P. Eckelman , John C. Timmer , Chelsie Macedo , Kyle S. Jones , Abrahim Hussain , Amir S. Razai , Bryan Becklund , Rajay Pandit , Mike Kaplan , Lucas Rascon , Quinn Deveraux
IPC分类号： C07K16/28
摘要： This invention relates generally to molecules that specifically engage 41BB, a member of the TNF receptor superfamily (TNFRSF). More specifically, this invention relates to multivalent and multispecific molecules that bind at least 41BB.
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公开(公告)号：US20220064318A1
公开(公告)日：2022-03-03
申请号：US17394900
申请日：2021-08-05
申请人： Inhibrx, Inc.
发明人： John C. Timmer , Kyle S. Jones , Amir S. Razai , Abrahim Hussain , Katelyn M. Willis , Quinn Deveraux , Brendan P. Eckelman
IPC分类号： C07K16/28 , A61K39/395
摘要： The disclosure relates generally to molecules that specifically engage death receptor 5 (DR5), a member of the TNF receptor superfamily (TNFRSF). More specifically the disclosure relates to multivalent and multispecific molecules that bind at least DR5.
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公开(公告)号：US20190263916A1
公开(公告)日：2019-08-29
申请号：US16295332
申请日：2019-03-07
申请人： Inhibrx, Inc.
发明人： Brendan P. Eckelman , John C. Timmer , Chelsie Hata , Kyle S. Jones , Abrahim Hussain , Amir S. Razai , Bryan Becklund , Rajay Pandit , Mike Kaplan , Lucas Rason , Quinn Deveraux
IPC分类号： C07K16/28
摘要： This invention relates generally to molecules that specifically engage OX40, a member of the TNF receptor superfamily (TNFRSF). More specifically this invention relates to multivalent and multispecific molecules that bind at least OX40.
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公开(公告)号：US10308720B2
公开(公告)日：2019-06-04
申请号：US15213296
申请日：2016-07-18
申请人： Inhibrx, Inc.
发明人： John C. Timmer , Kyle S. Jones , Amir S. Razai , Abrahim Hussain , Katelyn M. Willis , Quinn Deveraux , Brendan P. Eckelman
摘要： The disclosure relates generally to molecules that specifically engage death receptor 5 (DR5), a member of the TNF receptor superfamily (TNFRSF). More specifically the disclosure relates to multivalent and multispecific molecules that bind at least DR5.
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公开(公告)号：US20230416387A1
公开(公告)日：2023-12-28
申请号：US18067484
申请日：2022-12-16
申请人： Inhibrx, Inc.
发明人： Brendan P. Eckelman , John C. Timmer , Chelsie Macedo , Kyle S. Jones , Abrahim Hussain , Amir S. Razai , Bryan Becklund , Rajay Pandit , Mike Kaplan , Lucas Rascon , Quinn Deveraux
IPC分类号： C07K16/28
CPC分类号： C07K16/2878 , C07K16/2827 , C07K2317/33 , C07K2317/92 , C07K2317/75 , C07K2317/35 , C07K2317/52 , C07K2319/00 , C07K2317/24 , C07K2317/31 , C07K2317/569 , C07K2317/76
摘要： This invention relates generally to molecules that specifically engage 41BB, a member of the TNF receptor superfamily (TNFRSF). More specifically, this invention relates to multivalent and multispecific molecules that bind at least 41BB.
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公开(公告)号：US20220106397A1
公开(公告)日：2022-04-07
申请号：US17398851
申请日：2021-08-10
申请人： Inhibrx, Inc.
发明人： Brendan P. Eckelman , John C. Timmer , Chelsie Macedo , Kyle S. Jones , Abrahim Hussain , Amir S. Razai , Bryan Becklund , Rajay Pandit , Mike Kaplan , Lucas Rascon , Quinn Deveraux
摘要： This invention relates generally to molecules that specifically engage OX40, a member of the TNF receptor superfamily (TNFRSF). More specifically this invention relates to multivalent and multispecific molecules that bind at least OX40.
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9.发明授权公开(公告)号：US11117973B2
公开(公告)日：2021-09-14
申请号：US16387754
申请日：2019-04-18
申请人： Inhibrx, Inc.
发明人： John C. Timmer , Kyle S. Jones , Amir S. Razai , Abrahim Hussain , Katelyn M. Willis , Quinn Deveraux , Brendan P. Eckelman
IPC分类号： A61K39/395 , C07K16/28 , A61K39/00
摘要： The disclosure relates generally to molecules that specifically engage death receptor 5 (DR5), a member of the TNF receptor superfamily (TNFRSF) and methods of treatment. More specifically the disclosure relates to multivalent and multispecific molecules that bind at least DR5.
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公开(公告)号：US20190309083A1
公开(公告)日：2019-10-10
申请号：US16387754
申请日：2019-04-18
申请人： Inhibrx, Inc.
发明人： John C. Timmer , Kyle S. Jones , Amir S. Razai , Abrahim Hussain , Katelyn M. Willis , Quinn Deveraux , Brendan P. Eckelman
IPC分类号： C07K16/28
摘要： The disclosure relates generally to molecules that specifically engage death receptor 5 (DR5), a member of the TNF receptor superfamily (TNFRSF). More specifically the disclosure relates to multivalent and multispecific molecules that bind at least DR5.
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