公开(公告)号：US20230063066A1

公开(公告)日：2023-03-02

申请号：US16959653

申请日：2018-12-21

申请人： Kai WANG ,  Yong ZHOU ,  Shizhen QIN ,  Xiaogang WU ,  Institute for Systems Biology

发明人： Kai WANG ,  Yong ZHOU ,  Shizhen QIN ,  Xiaogang WU

IPC分类号： C12Q1/6883 ,  G01N33/569

摘要： Reagents and methods to use said reagents for detection of markers of various aspects of Lyme disease have been identified in biological fluids thus permitting diagnosis or classification of Lyme disease subjects as well as indicating suitable methods of treatment.

公开(公告)号：US20140073524A1

公开(公告)日：2014-03-13

申请号：US14020626

申请日：2013-09-06

申请人： Institute for Systems Biology

发明人： Leroy HOOD ,  Kai WANG ,  Inyoul LEE ,  Yong ZHOU ,  Ji Hoon CHO ,  Dhimankrishna GHOSH

IPC分类号： C12Q1/68 ,  G01N33/68

CPC分类号： C12Q1/6883 ,  C12Q1/6886 ,  C12Q2600/158 ,  C12Q2600/178 ,  G01N33/6896 ,  G01N2800/30

摘要： Concentrations of certain miRNA, mRNA and/or protein markers in the biological fluids and/or tissues of a subject are used to determine the probability that the subject does or does not have Posttraumatic Stress Disorder (PTSD). The concentrations of these markers in fluids and/or tissues are different in subjects with PTSD as compared to subjects who do not suffer from this disorder.

摘要翻译： 使用受试者的生物流体和/或组织中某些miRNA，mRNA和/或蛋白质标记物的浓度来确定受试者做或不具有创伤后应激障碍（PTSD）的可能性。 与不患有这种疾病的受试者相比，这些标记物在流体和/或组织中的浓度与具有PTSD的受试者不同。