专利检索 ap:("Integrated Biotherapeutics, Inc." OR "University of Maryland, College Park" OR "University of Maryland, Baltimore" OR "La Jolla Institute for Immunology") AND inv:"Yimeng Wang" 第 1 页

1.

发明公开
BROADLY NEUTRALIZING BINDING MOLECULES AGAINST MARBURGVIRUSES 审中-公开

公开(公告)号：US20230235029A1

公开(公告)日：2023-07-27

申请号：US18016930

申请日：2021-07-20

申请人： Integrated Biotherapeutics, Inc. , University of Maryland, College Park , University of Maryland, Baltimore , La Jolla Institute for Immunology

发明人： Mohammad Javad Aman , Yimeng Wang , Shweta Kailasan , Xuelian Zhao , Andrey Galkin , Katie A. Howell , Erica Ollmann Saphire , Yuxing Li

IPC分类号： C07K16/10 , A61P31/14 , G01N33/569 , G01N33/543

CPC分类号： C07K16/10 , A61P31/14 , G01N33/56983 , G01N33/54386 , A61K39/00

摘要： Disclosed herein is a novel class of isolated binding molecules including monoclonal antibodies that targets a broadly conserved epitope within the marburgvirus species. Certain aspects provide an effective treatment option for hemorrhagic fever caused by marburgviruses.