公开(公告)号：US12018020B2

公开(公告)日：2024-06-25

申请号：US17311560

申请日：2019-12-12

申请人： Intervet Inc.

发明人： Christophe Pierre Alain Chassaing ,  Xiaoling Jin ,  Rositza Iordanova Petrova ,  Richard J. Varsolona ,  Lorenzo Codan ,  Edward Cleator ,  Adrian Goodyear ,  Jonathan Simmons ,  Tanja Schweisel

IPC分类号： C07D405/14

CPC分类号： C07D405/14 ,  C07B2200/13

摘要： The present application relates to crystalline forms of 1-[(3R,4S)-4-cyanotetrahydropyran-3-yl]-3-[(2-fluoro-6-methoxy-4-pyridyl) amino]pyrazole-4-carboxamide and processes for the preparation thereof. The compound is useful for the treatment of JAK-mediated diseases or conditions such as atopic dermatitis.

公开(公告)号：US20220024902A1

公开(公告)日：2022-01-27

申请号：US17311560

申请日：2019-12-12

申请人： Intervet Inc.

发明人： Christophe Pierre Alain Chassaing ,  Xiaoling Jin ,  Rositza Iordanova Petrova ,  Richard J. Varsolona ,  Lorenzo Codan ,  Edward Cleator ,  Adrian Goodyear ,  Jonathan Simmons ,  Tanja Schweisel

IPC分类号： C07D405/14

摘要： The present application relates to crystalline forms of 1-[(3R,4S)-4-cyanotetrahydropyran-3-yl]-3-[(2-fluoro-6-methoxy-4-pyridyl) amino]pyrazole-4-carboxamide and processes for the preparation thereof. The compound is useful for the treatment of JAK-mediated diseases or conditions such as atopic dermatitis.