公开(公告)号：US20240010964A1

公开(公告)日：2024-01-11

申请号：US18348689

申请日：2023-07-07

Applicant: Iowa State University Research Foundation, Inc.

Inventor： Shan Jiang ,  Kyle Miller ,  Connor Phelps Thorpe ,  Alan Eggenberger ,  Kan Wang

IPC: C12M1/42 ,  C12N15/89

CPC classification number: C12M35/00 ,  C12N15/895

Abstract: Improved biolistic bombardment is observable when using a modification to a double-barrel device. One such modification is a custom attachment that can be retrofit to a standard helium-based gene gun. The custom attachment facilitates DNA and protein delivery. The attachment confines the flow of particles in a barrel similar to the choke on a shotgun barrel.

公开(公告)号：US20140096284A1

公开(公告)日：2014-04-03

申请号：US13785433

申请日：2013-03-05

Applicant: Iowa State University Research Foundation, Inc.

Inventor： Susana Martin-Ortigosa ,  Kan Wang

IPC: C12N15/82 ,  C12N15/63 ,  A61K9/50

CPC classification number: C12N15/8207 ,  A61K9/5089 ,  A61K9/5115 ,  A61K2039/54 ,  C12N15/63 ,  C12N15/895

Abstract: The invention provides particles and methods to deliver freeze- or air-dried molecules to cells.

Abstract translation: 本发明提供了将冷冻或风干分子递送至细胞的颗粒和方法。