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公开(公告)号：US09439943B2
公开(公告)日：2016-09-13
申请号：US14844128
申请日：2015-09-03
申请人： Ipsen Pharma S.A.S.
摘要： The present invention relates to peptide ligands of the melanocortin receptors, in particular the melancortin-4 receptor, and as such, are useful in the treatment of disorders responsive to the activation of this receptor, such as insulin resistance.
摘要翻译： 本发明涉及黑皮质素受体，特别是melancortin-4受体的肽配体，因此可用于治疗对该受体的活化反应的病症，例如胰岛素抵抗。
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公开(公告)号：US20150366934A1
公开(公告)日：2015-12-24
申请号：US14844128
申请日：2015-09-03
申请人： IPSEN PHARMA S.A.S.
IPC分类号： A61K38/12
摘要： The present invention relates to peptide ligands of the melanocortin receptors, in particular the melancortin-4 receptor, and as such, are useful in the treatment of disorders responsive to the activation of this receptor, such as insulin resistance.
摘要翻译： 本发明涉及黑皮质素受体，特别是melancortin-4受体的肽配体，并且因此可用于治疗对该受体的活化反应的病症，例如胰岛素抵抗。
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3.发明申请METHOD FOR INHIBITING INFLAMMATION and PRO-INFLAMMATORY CYTOKINE/CHEMOKINE EXPRESSION USING A GHRELIN ANALOGUE 审中-公开使用GHRELIN模拟抑制炎症和促炎细胞因子/ CHEMOKINE表达的方法公开(公告)号：US20150111823A1
公开(公告)日：2015-04-23
申请号：US14524088
申请日：2014-10-27
申请人： IPSEN PHARMA S.A.S.
IPC分类号： C07K7/06
CPC分类号： A61K38/22 , A61K38/05 , A61K38/06 , A61K38/25 , C07K7/06 , Y02A50/41 , Y02A50/412 , Y02A50/423 , Y02A50/463 , Y02A50/475 , Y02A50/484
摘要： The present invention provides a method of ameliorating inflammation, inhibiting proinflammatory cytokine and/or chemokine expression and treating various diseases and/or conditions incidental to the onset of inflammation, in a subject in need of treatment for such conditions, by administering select analogues of native hGhrelin.
摘要翻译： 本发明提供了一种在需要治疗这些病症的受试者中通过施用天然的选择性类似物来改善炎症，抑制促炎细胞因子和/或趋化因子表达并且治疗与发作炎症相关的各种疾病和/或病症的方法 hGhrelin。
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公开(公告)号：US09827286B2
公开(公告)日：2017-11-28
申请号：US15242866
申请日：2016-08-22
申请人： Ipsen Pharma S.A.S.
摘要： The present invention relates to peptide ligands of the melanocortin receptors, in particular the melancortin-4 receptor, and as such, are useful in the treatment of disorders responsive to the activation of this receptor, such as insulin resistance.
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5.发明申请公开(公告)号：US20160206700A1
公开(公告)日：2016-07-21
申请号：US14997678
申请日：2016-01-18
申请人： Ipsen Pharma S.A.S.
CPC分类号： A61K38/22 , A61K38/05 , A61K38/06 , A61K38/25 , C07K7/06 , Y02A50/41 , Y02A50/412 , Y02A50/423 , Y02A50/463 , Y02A50/475 , Y02A50/484
摘要： The present invention provides a method of ameliorating inflammation, inhibiting proinflammatory cytokine and/or chemokine expression and treating various diseases and/or conditions incidental to the onset of inflammation, in a subject in need of treatment for such conditions, by administering select analogues of native hGhrelin.
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