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12 条记录 (耗时 0.018 秒)

    Dithiocarbamate compounds
    1.
    发明授权
    Dithiocarbamate compounds 失效
    二硫代氨基甲酸酯化合物

    公开(公告)号：US5130473A

    公开(公告)日：1992-07-14

    申请号：US638268

    申请日：1991-01-07

    申请人： Irwin C. Jacobs ,  Neil E. S. Thompson

    发明人： Irwin C. Jacobs ,  Neil E. S. Thompson

    IPC分类号： C09K8/524

    CPC分类号： C09K8/524

    摘要： Reduction of asphaltene precipitation in asphaltenic subterranean reservoirs treated with aqueous solutions of strong acid is achieved by utilizing novel dithiocarbamate compositions to sequester iron.

    摘要翻译： 通过使用新的二硫代氨基甲酸盐组合物螯合铁来实现用强酸水溶液处理的沥青质地下储层中沥青质沉淀的降低。

    Formulations and use of controlled-release indole alkaloids
    3.
    发明授权
    Formulations and use of controlled-release indole alkaloids 有权
    控制释放吲哚生物碱的配方和使用

    公开(公告)号：US06416793B1

    公开(公告)日：2002-07-09

    申请号：US09614007

    申请日：2000-07-11

    申请人： Michael A. Zeligs ,  Irwin C. Jacobs

    发明人： Michael A. Zeligs ,  Irwin C. Jacobs

    IPC分类号： A61K3578

    CPC分类号： A61K9/5036 ,  A61K9/5057 ,  A61K31/475 ,  A61K31/55

    摘要： The present invention relates to spray dried hydrophobic phytochemical (i.e., yohimbine and ibogaine) compositions, a process for making such compositions and a method of using such compositions for, e.g., the promotion of weight loss. Typically, the hydrophobic dietary compositions of the present invention exhibit enhanced absorptivity when taken orally.

    摘要翻译： 本发明涉及喷雾干燥的疏水植物化学（即育亨宾和伊泊加因）组合物，制备这种组合物的方法和使用这种组合物的方法，例如促进体重减轻。 通常，当口服时，本发明的疏水性膳食组合物表现出增强的吸收性。

    SOLID PARTICULATE COMPOSITIONS COMPRISING COENZYME Q10
    5.
    发明申请
    SOLID PARTICULATE COMPOSITIONS COMPRISING COENZYME Q10 有权
    包含COENZYME Q10的固体颗粒组合物

    公开(公告)号：US20130330408A1

    公开(公告)日：2013-12-12

    申请号：US14000902

    申请日：2012-03-16

    申请人： Irwin C. Jacobs

    发明人： Irwin C. Jacobs

    IPC分类号： A61K9/16 ,  A61K31/122

    CPC分类号： A61K31/122 ,  A61K9/107 ,  A61K9/16 ,  A61K9/1617 ,  A61K9/1652

    摘要： The present invention generally relates to improvements in the bioavailability and/or solubility of coenzyme Q10. For example, the present invention relates to methods for preparing particulate compositions including coenzyme Q10 that generally comprise dispersing and/or dissolving the coenzyme Q10 throughout a suitable solvent, and combining the coenzyme Q10 and an encapsulating (e.g., microencapsulating) agent. The present invention also generally relates to particulate compositions comprising coenzyme Q10 that exhibit improved bioavailability and/or solubility as compared to previous coenzyme Q10 products.

    摘要翻译： 本发明一般涉及辅酶Q10的生物利用度和/或溶解度的改善。 例如，本发明涉及用于制备包括辅酶Q10的颗粒组合物的方法，其通常包括将辅酶Q10分散和/或溶解在整个合适的溶剂中，以及将辅酶Q10和包封（例如微胶囊化）试剂混合。 本发明还通常涉及包含与先前的辅酶Q10产物相比显示出改善的生物利用度和/或溶解度的辅酶Q10的颗粒组合物。

    Compositions and methods of adjusting steroid hormone metabolism through phytochemicals
    8.
    发明授权
    Compositions and methods of adjusting steroid hormone metabolism through phytochemicals 失效
    通过植物化学调节类固醇激素代谢的组成和方法

    公开(公告)号：US6086915A

    公开(公告)日：2000-07-11

    申请号：US53180

    申请日：1998-04-01

    申请人： Michael A. Zeligs ,  Irwin C. Jacobs

    发明人： Michael A. Zeligs ,  Irwin C. Jacobs

    IPC分类号： A61K9/16 ,  A61K36/752 ,  A61K9/66

    CPC分类号： A61K9/1617 ,  A61K9/1652

    摘要： The present invention relates to spray dried hydrophobic phytochemical chemopreventative compositions, a process for making such compositions and a method of using such compositions to adjust steroid metabolism in mammals. Typically, the hydrophobic dietary compositions of the present invention exhibit enhanced absorptivity when taken orally as a chemopreventative agent.

    摘要翻译： 本发明涉及喷雾干燥的疏水性植物化学化学预防组合物，制备这种组合物的方法和使用这些组合物调节哺乳动物中类固醇代谢的方法。 通常，当作为化学预防剂口服时，本发明的疏水性膳食组合物表现出增强的吸收性。

    Solid particulate compositions comprising coenzyme Q10
    9.
    发明授权
    Solid particulate compositions comprising coenzyme Q10 有权

    公开(公告)号：US09655849B2

    公开(公告)日：2017-05-23

    申请号：US14000902

    申请日：2012-03-16

    申请人： Irwin C. Jacobs

    发明人： Irwin C. Jacobs

    IPC分类号： A61K9/16 ,  A61K31/122 ,  A61K9/107

    CPC分类号： A61K31/122 ,  A61K9/107 ,  A61K9/16 ,  A61K9/1617 ,  A61K9/1652

    摘要： The present invention generally relates to improvements in the bioavailability and/or solubility of coenzyme Q10. For example, the present invention relates to methods for preparing particulate compositions including coenzyme Q10 that generally comprise dispersing and/or dissolving the coenzyme Q10 throughout a suitable solvent, and combining the coenzyme Q10 and an encapsulating (e.g., microencapsulating) agent. The present invention also generally relates to particulate compositions comprising coenzyme Q10 that exhibit improved bioavailability and/or solubility as compared to previous coenzyme Q10 products.

    Method of producing porous tablets with improved dissolution properties
    10.
    发明授权
    Method of producing porous tablets with improved dissolution properties 失效

    公开(公告)号：US06544552B2

    公开(公告)日：2003-04-08

    申请号：US09757426

    申请日：2001-01-11

    申请人： Robert E. Sparks ,  Irwin C. Jacobs ,  Norbert S. Mason

    发明人： Robert E. Sparks ,  Irwin C. Jacobs ,  Norbert S. Mason

    IPC分类号： A61K920

    CPC分类号： A61K9/0056 ,  A61K9/2095 ,  Y10S514/951 ,  Y10S514/96

    摘要： A method of producing a fast-dissolving pharmaceutical delivery device of moderate strength. The delivery device is a fully formed tablet composed of readily available sugars, strength polymers and a volatilizable excipient along with an active ingredient and optional flavorings. The tablet as made will disintegrate in an aqueous medium such as saliva in under 15 seconds, making mastication unnecessary or at least requiring only one or two bites on the tablet. Essential to the invention is the easily obtainable particle size ranges of the sugars and the volatilizable excipient which promotes optimum release and tablet strength. The invention also allows for effective taste masking of the active ingredient with standard particle coating techniques.