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公开(公告)号:US4927639A
公开(公告)日:1990-05-22
申请号:US305082
申请日:1989-02-02
CPC分类号: A61K31/19 , A61K9/2081
摘要: A disintegratable formulation of gemfibrozil providing both immediate and sustained release and comprises a tablet compressed from a mixture of a first and second granulation, and a disintegration excipient operable to effect partial or complete disintegration in the stomach. The first granulation comprises finely divided particles of pure gemfibrozil granulated with at least one cellulose derivative and the second granulation comprises finely divided particles of pure gemfibrozil granulated with a pharmaceutically acceptable water soluble or insoluble polymer which are then uniformly coated with a pharmaceutically acceptable (meth)acrylate copolymer prior to admixture with the first granulation. The first and second granulations are present in the final composition in a ratio of from about 10:1 to about 1:10.
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公开(公告)号:US4814354A
公开(公告)日:1989-03-21
申请号:US912903
申请日:1986-09-26
CPC分类号: A61K9/5042 , A61K31/785 , A61K9/0056
摘要: Cholestyramine can be administered orally along with one or more other lipid regulating agent(s) and/or other beneficial agent(s) in compositions in which the cholestyramine has been suitably pretreated.
摘要翻译: 在已经适当预处理消胆胺的组合物中,胆钙清蛋白可以与一种或多种其它脂质调节剂和/或其它有益剂一起口服给药。
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公开(公告)号:US4971804A
公开(公告)日:1990-11-20
申请号:US305081
申请日:1989-02-02
CPC分类号: A61K31/19 , A61K9/5073
摘要: A water-dispersible formulation of gemfibrozil comprising finely divided particles of pure gemfibrozil uniformly coated with a mixture of a wax and at least one hydrophilic material, the coated particles in turn being overcoated with a minor amount of a surfactant.
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公开(公告)号:US4600645A
公开(公告)日:1986-07-15
申请号:US696955
申请日:1985-01-31
CPC分类号: A61K9/5073 , Y10T428/2991 , Y10T428/2998
摘要: The problems of tackiness and long curing times usually associated with the treatment of dosage forms are overcome via the use of a new curing process. That process involves: (1) coating a drug with a sustained release formulation, (2) immediately coating with a water-soluble overcoat, (3) drying, and (4) recovering the coated dosage form.
摘要翻译: 通过使用新的固化方法克服了通常与剂型治疗相关的粘着性和长的固化时间的问题。 该方法包括:(1)用持续释放制剂涂覆药物,(2)立即用水溶性外涂层涂覆,(3)干燥,和(4)回收涂覆的剂型。
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公开(公告)号:US5924718A
公开(公告)日:1999-07-20
申请号:US704444
申请日:1996-08-27
申请人: Robert H. Gordon , Jack E. Spector , Mario Serrano
发明人: Robert H. Gordon , Jack E. Spector , Mario Serrano
摘要: A recreational board which adapted to be ridden by a user has a thermoplastic upper portion with an outer surface and an inner surface, a thermoplastic lower portion including a plurality of flanges, is bonded together by joining the plurality of flanges to the inner surface of the upper portion.
摘要翻译: 适于被使用者骑乘的休闲板具有外表面和内表面的热塑性上部,包括多个凸缘的热塑性下部通过将多个凸缘接合到所述多个凸缘的内表面而结合在一起 上部。
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公开(公告)号:USD268911S
公开(公告)日:1983-05-10
申请号:US262345
申请日:1981-05-11
申请人: Robert H. Gordon
设计人: Robert H. Gordon
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