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公开(公告)号：US3981865A
公开(公告)日：1976-09-21
申请号：US586015
申请日：1975-06-11
申请人： Isamu Saikawa , Shuntaro Takano , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Kyoko Kasuya , Yutaka Kodama
发明人： Isamu Saikawa , Shuntaro Takano , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Kyoko Kasuya , Yutaka Kodama
IPC分类号： C07D499/00 , C07D499/44 , C07D499/48 , C07D499/64 , C07D499/68 , C07D499/66 , C07D499/70
CPC分类号： C07D499/00
摘要： Novel bis-type penicillins containing a (thio)acylureido group in the molecule, which are valuable antibacterial compounds for use in mammals including a human being.This disclosure relates to such compounds and a process for the preparation thereof.
摘要翻译： 在分子中含有（硫代）酰基脲基的新型双型青霉素，其是用于哺乳动物（包括人）的有价值的抗菌化合物。
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2.发明授权
公开(公告)号：US4110327A
公开(公告)日：1978-08-29
申请号：US732860
申请日：1976-10-15
申请人： Isamu Saikawa , Shuntaro Takano , Chosaku Yoshida , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Yutaka Kodama
发明人： Isamu Saikawa , Shuntaro Takano , Chosaku Yoshida , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Yutaka Kodama
IPC分类号： C07D499/00 , C07D499/64 , C07D501/20 , C07D241/08 , C07D401/12 , C07D401/14 , C07D413/12
CPC分类号： C07D499/00
摘要： Novel penicillins and cephalosporins and non-toxic salts thereof, which contain a mono- or di-oxo- or thioxo-piperazino(thio)carbonylamino group in molecule. These compounds are valuable antibacterial compounds for use in mammals including man. This disclosure relates to such compounds and a process for the preparation thereof.
摘要翻译： 新型青霉素和头孢菌素及其无毒盐，其在分子中含有一个或二个氧代或二硫代哌嗪子基（硫代）羰基氨基。 这些化合物是用于包括人在内的哺乳动物的有价值的抗菌化合物。 本公开涉及这些化合物及其制备方法。
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公开(公告)号：US4379152A
公开(公告)日：1983-04-05
申请号：US39904
申请日：1979-05-17
申请人： Isamu Saikawa , Shuntaro Takano , Chosaku Yoshida , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Yutaka Kodama
发明人： Isamu Saikawa , Shuntaro Takano , Chosaku Yoshida , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Yutaka Kodama
IPC分类号： C07D241/08 , C07D499/00 , C07D501/22 , C07D501/26 , A61K31/545
CPC分类号： C07D241/08 , C07D499/00
摘要： Novel penicillins and cephalosporins and non-toxic salts thereof, which contain a mono- or di-oxo- or thioxo-piperazino(thio)carbonylamino group in molecule. These compounds are valuable antibacterial compounds for use in mammals including man. This disclosure relates to such compounds and a process for the preparation thereof.
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公开(公告)号：US4327097A
公开(公告)日：1982-04-27
申请号：US47818
申请日：1979-06-12
申请人： Isamu Saikawa , Shuntaro Takano , Chosaku Yoshida , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Yutaka Kodama
发明人： Isamu Saikawa , Shuntaro Takano , Chosaku Yoshida , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Yutaka Kodama
IPC分类号： C07D241/08 , C07D499/00 , C07D499/64 , A61K31/495 , C07D499/70
CPC分类号： C07D241/08 , C07D499/00
摘要： Novel penicillins and cephalosporins and non-toxic salts thereof, which contain a mono- or di-oxo- or thioxo-piperazino(thio)carbonylamino group have been prepared. These compounds are valuable anti-bacterial compounds for use in mammals including man. A process for the preparation of the compounds has also been discovered.
摘要翻译： 已经制备了含有单 - 或二 - 氧代或硫代 - 哌嗪子基（硫代）羰基氨基的新型青霉素和头孢菌素及其无毒盐。 这些化合物是用于包括人在内的哺乳动物的有价值的抗菌化合物。 还已经发现了制备化合物的方法。
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公开(公告)号：US4219554A
公开(公告)日：1980-08-26
申请号：US915873
申请日：1978-06-15
申请人： Isamu Saikawa , Shuntaro Takano , Chosaku Yoshida , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Yutaka Kodama
发明人： Isamu Saikawa , Shuntaro Takano , Chosaku Yoshida , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Yutaka Kodama
IPC分类号： C07D241/08 , C07D499/00 , C07D499/64 , C07D501/20 , A61K31/43 , C07D499/68
CPC分类号： C07D499/00 , C07D241/08
摘要： Novel penicillins and non-toxic salts thereof, which contain a mono- or di-oxo- or thioxo-piperazino(thio)carbonylamino group have been prepared. These compounds are valuable antibacterial compounds for use in mammals including man. A process for the preparation of the compounds has also been discovered.
摘要翻译： 已经制备了含有单 - 或二 - 氧代 - 或硫代 - 哌嗪子基（硫代）羰基氨基的新型青霉素及其无毒盐。 这些化合物是用于包括人在内的哺乳动物的有价值的抗菌化合物。 还已经发现了制备化合物的方法。
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公开(公告)号：US4112090A
公开(公告)日：1978-09-05
申请号：US654060
申请日：1976-01-30
申请人： Isamu Saikawa , Shuntaro Takano , Chosaku Yoshida , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Yutaka Kodama
发明人： Isamu Saikawa , Shuntaro Takano , Chosaku Yoshida , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Yutaka Kodama
IPC分类号： C07D499/00 , C07D499/64 , C07D501/20 , A61K31/43 , C07D499/66 , C07D499/68 , C07D499/70
CPC分类号： C07D499/00
摘要： Novel penicillins and cephalosporins and non-toxic salts thereof, which contain a mono- or di-oxo- or thioxo-piperazino(thio)carbonylamino group have been prepared. These compounds are valuable antibacterial compounds for use in mammals including man. A process for the preparation of the compounds has also been discovered.
摘要翻译： 已经制备了含有单 - 或二 - 氧代或硫代 - 哌嗪子基（硫代）羰基氨基的新型青霉素和头孢菌素及其无毒盐。 这些化合物是用于包括人在内的哺乳动物的有价值的抗菌化合物。 还已经发现了制备化合物的方法。
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公开(公告)号：US4087424A
公开(公告)日：1978-05-02
申请号：US571479
申请日：1975-04-24
申请人： Isamu Saikawa , Shuntaro Takano , Chosaku Yoshida , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Yutaka Kodama
发明人： Isamu Saikawa , Shuntaro Takano , Chosaku Yoshida , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Yutaka Kodama
IPC分类号： C07D241/08 , C07D499/00 , C07D499/46 , C07D499/64 , C07D501/20 , C07D501/24
CPC分类号： C07D499/00 , C07D241/08
摘要： Novel penicillins and cephalosporins and non-toxic salts thereof, which contain a mono- or di-oxo- or thioxo-piperazino(thio)carbonylamino group in molecule. These compounds are valuable antibacterial compounds for use in mammals including man. This disclosure relates to such compounds and a process for the preparation thereof.
摘要翻译： 新型青霉素和头孢菌素及其无毒盐，其在分子中含有一个或二个氧代或二硫代哌嗪子基（硫代）羰基氨基。 这些化合物是用于包括人在内的哺乳动物的有价值的抗菌化合物。 本公开涉及这些化合物及其制备方法。
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公开(公告)号：US4410522A
公开(公告)日：1983-10-18
申请号：US841608
申请日：1977-10-12
申请人： Isamu Saikawa , Shuntaro Takano , Chosaku Yoshida , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Yutaka Kodama
发明人： Isamu Saikawa , Shuntaro Takano , Chosaku Yoshida , Okuta Takashima , Kaishu Momonoi , Seietsu Kuroda , Miwako Komatsu , Takashi Yasuda , Yutaka Kodama
IPC分类号： C07D241/08 , C07D499/00 , C07D501/20 , A61K31/545 , C07D501/56
CPC分类号： C07D241/08 , C07D499/00
摘要： Novel penicillins and cephalosporins and non-toxic salts thereof, which contain a mono- or di-oxo- or thioxo-piperazino(thio)carbonylamino group in molecule. These compounds are valuable antibacterial compounds for use in mammals including man. This disclosure relates to such compounds and a process for the preparation thereof.
摘要翻译： 新型青霉素和头孢菌素及其无毒盐，其在分子中含有一个或二个氧代或二硫代哌嗪子基（硫代）羰基氨基。 这些化合物是用于包括人在内的哺乳动物的有价值的抗菌化合物。 本公开涉及这些化合物及其制备方法。
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