公开(公告)号：US4533637A

公开(公告)日：1985-08-06

申请号：US379369

申请日：1982-05-18

申请人： Isao Yamane ,  Mikio Kan ,  Yoshiki Minamoto

发明人： Isao Yamane ,  Mikio Kan ,  Yoshiki Minamoto

IPC分类号： C12N5/06 ,  A61K38/21 ,  A61P43/00 ,  C07K14/555 ,  C12N5/00 ,  C12P21/00 ,  C12R1/91

CPC分类号： C07K14/555 ,  C12N5/0037 ,  C12N2500/36 ,  Y10S435/948

摘要： On the new findings that cyclodextrin shows no cytotoxicity or only slight cytotoxicity on cell growth and that lipophilic substances such as unsaturated fatty acids and lipophilic vitamins when present together with, or included in, cyclodextrin show such effects as cell growth promoting effect and accelerating effect of the productivity of valuable products, a serum-free or serum-reduced culture medium or a substitute composition for serum for a culture medium comprising a cyclodextrin and at least one lipophilic nutrient substance, said cyclodextrin and said lipophilic nutrient substance being preferably in the form of inclusion complex between them, is provided.

摘要翻译： 关于环糊精对细胞生长没有细胞毒性或细胞毒性的新发现，当与环糊精一起存在或包含在环糊精中时，亲脂性物质如不饱和脂肪酸和亲脂性维生素显示出如细胞生长促进作用和加速效果 有价值产品的生产率，无血清或血清减少的培养基或用于包含环糊精和至少一种亲脂性营养物质的培养基的血清替代组合物，所述环糊精和所述亲脂性营养物质优选为 提供它们之间的包合物。