公开(公告)号：US20090124672A1

公开(公告)日：2009-05-14

申请号：US12266288

申请日：2008-11-06

申请人： Ivan Diamond ,  David Overstreet

发明人： Ivan Diamond ,  David Overstreet

IPC分类号： A61K31/4245 ,  A61P25/24

CPC分类号： A61K31/352 ,  A61K31/4245

摘要： Disclosed are isoflavone derivatives having the structure of Formula I which are useful as ALDH-2 inhibitors for use treating in mammals suffering from psychiatric disorders such as, for example, depression, generalized anxiety, social phobia, panic disorder, and sleep disorders.

摘要翻译： 公开了具有式I结构的异黄酮衍生物，其可用作用于治疗患有精神病障碍（例如抑郁症，广泛性焦虑症，社交恐惧症，惊恐障碍和睡眠障碍）的哺乳动物的ALDH-2抑制剂。

公开(公告)号：US20050233870A1

公开(公告)日：2005-10-20

申请号：US10825715

申请日：2004-04-16

申请人： Steven Gattis ,  David Overstreet

发明人： Steven Gattis ,  David Overstreet

IPC分类号： A63B21/02 ,  A63B22/00 ,  A63B53/06 ,  A63B53/16 ,  A63B69/00 ,  A63B69/20 ,  A63B69/34

CPC分类号： A63B21/02 ,  A63B21/4047 ,  A63B69/004 ,  A63B69/20 ,  A63B2225/093

摘要： A training pad apparatus and method for follow-through striking with consistent resistance, positioning and resetting. A training, or striking, pad is connected to a training pad arm, which is in turn connected to a pivot assembly. The pivot assembly includes a pivotal connection member that is fixed in position and is pivotally connected to an end of the training pad arm opposite the training pad. The pivot assembly also includes elongated elastic members that provide a resisting force in a plane approximately orthogonal to the length of the training pad arm. An enclosure houses the pivot assembly and defines an opening through which the training pad arm extends. Optional positioning poles extend in a parallel manner through the enclosure and provide a means for slidably adjusting the position of training pad along the length of the poles.

摘要翻译： 一种用于后续打击的训练垫装置和方法，具有一致的阻力，定位和重置。 训练垫或打击垫连接到训练垫臂上，训练垫臂又连接到枢轴组件。 枢转组件包括枢转连接构件，该枢转连接构件固定在适当位置并且枢转地连接到与训练垫相对的训练垫臂的端部。 枢转组件还包括细长的弹性构件，其在大致垂直于训练垫臂的长度的平面中提供抵抗力。 外壳容纳枢转组件并且限定训练垫臂延伸通过的开口。 可选的定位杆以平行方式延伸通过外壳，并提供用于沿着杆的长度可滑动地调节训练垫的位置的装置。

公开(公告)号：US5783189A

公开(公告)日：1998-07-21

申请号：US636347

申请日：1996-04-23

申请人： Yue-Hu Pei ,  David Overstreet ,  Amir Hosein Rezvani ,  David Yue-Wei Lee

发明人： Yue-Hu Pei ,  David Overstreet ,  Amir Hosein Rezvani ,  David Yue-Wei Lee

IPC分类号： A61K36/48 ,  A61K39/385 ,  A61K35/78

CPC分类号： A61K36/48 ,  Y10S514/811

摘要： Isoflavonoids containing a carbon-carbon linked .beta.-D-glucose moiety at the C-8 position and isolated from the Chinese herbal plant Pueraria lobata are useful for treating alcohol dependence.

摘要翻译： 在C-8位置含有碳 - 碳连接的β-D-葡萄糖部分并从中草药植物葛根分离的异黄酮可用于治疗酒精依赖。