公开(公告)号：US20210284942A1

公开(公告)日：2021-09-16

申请号：US17252390

申请日：2019-06-21

申请人： Jérémie LAURENT ,  ASTRAVEUS ,  ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS ,  UNIVERSITE DE PARIS

发明人： Jérémie LAURENT ,  Nicolas JAMOND ,  Andrew SHAILER-SMITH ,  Laetitia PINTE

IPC分类号： C12M3/06 ,  C12M1/04 ,  C12M1/00

摘要： A microfluidic device for processing particles, including: an elongated chamber including elongated segment(s), input seeding channel(s) and one output seeding channel defining a seeding flow transverse to the longitudinal direction of the segment, input harvest channel(s) and one output harvest channel defining a harvest flow in the longitudinal direction, wherein, for the segment, a single input seeding tree defines input seeding channels and a single output seeding tree defines output seeding channels, junctions of the input seeding channels and output seeding channels with the processing chamber being distributed along the segment on both sides of the chamber, wherein: Rs_input ⁢ S 2 ⁢ 1 ( ∑ k ⁢ V k * S k ) / V TOTs ⁢ _ ⁢ inpu ⁢ t is higher than 50, S21 being the segment cross section perpendicular to the transverse direction, (Σk Vk*Sk)/VTOTs_input being, the sum of the products of the volume and the cross section of the input seeding channel, divided by the total volume V TOTs_input of the input seeding channels.