-
公开(公告)号:US06197783B1
公开(公告)日:2001-03-06
申请号:US09381617
申请日:1999-09-24
IPC分类号: A61K314375
CPC分类号: C07D471/14
摘要: Tetrahydropyrido compounds of formula (I) in which the substituents have the meanings mentioned in the description, are suitable for the prevention or treatment of gastrointestinal diseases.
摘要翻译: 其中取代基具有说明书中提及的含义的式(I)的四氢吡啶化合物适用于预防或治疗胃肠道疾病。
-
公开(公告)号:US07105676B2
公开(公告)日:2006-09-12
申请号:US10783512
申请日:2004-02-23
申请人: Jörg Senn-Bilfinger
发明人: Jörg Senn-Bilfinger
CPC分类号: C07D471/14
摘要: Compounds of formula (1) in which the substituents have the meanings mentioned in the description, are suitable for the prevention and treatment of gastrointestinal diseases.
-
公开(公告)号:US06653477B2
公开(公告)日:2003-11-25
申请号:US10182652
申请日:2002-09-19
申请人: Jörg Senn-Bilfinger , Wilm Buhr , Peter Zimmermann
发明人: Jörg Senn-Bilfinger , Wilm Buhr , Peter Zimmermann
IPC分类号: C07D4704
CPC分类号: C07D471/04
摘要: Compounds of formula (I), in which the substituents have the meanings mentioned in the description, are valuable intermediates for preparing active compounds for the prevention and treatment of gastrointestinal diseases.
摘要翻译: 其中取代基具有说明书中提及的含义的式(I)化合物是制备用于预防和治疗胃肠道疾病的活性化合物的有价值的中间体。
-
公开(公告)号:US07326718B2
公开(公告)日:2008-02-05
申请号:US10534741
申请日:2003-11-15
IPC分类号: C07D471/02 , C07D491/02 , C07D498/02 , A01N43/42 , A61K31/44
CPC分类号: C07D471/04
摘要: The present invention relates to 8-substituted imidazopyridines of a certain formula (1) in which the substitutents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.
摘要翻译: 本发明涉及具有式(1)的8-取代的咪唑并吡啶,其中取代基和符号具有说明书中所示的含义。 该化合物具有抑制胃分泌和优良的胃肠保护作用。
-
公开(公告)号:US07314935B2
公开(公告)日:2008-01-01
申请号:US10504432
申请日:2003-02-12
IPC分类号: C07D471/06 , A61K31/437
CPC分类号: C07D471/14
摘要: The invention relates to compounds of the formula (1) where the substituents and symbols are as defined in the description. The compounds are valuable intermediates for preparing active pharmaceutical ingredients.
摘要翻译: 本发明涉及式(1)的化合物,其中取代基和符号如说明书中所定义。 这些化合物是制备活性药物成分的有价值的中间体。
-
公开(公告)号:US06696460B2
公开(公告)日:2004-02-24
申请号:US10103733
申请日:2002-03-25
申请人: Jörg Senn-Bilfinger
发明人: Jörg Senn-Bilfinger
IPC分类号: A61K314375
CPC分类号: C07D471/14
摘要: Compounds of formula (1) in which the substituents have the meanings mentioned in the description, are suitable for the prevention and treatment of gastrointestinal diseases.
摘要翻译: 取代基具有说明书中提及的含义的式(1)化合物适用于预防和治疗胃肠道疾病。
-
公开(公告)号:US07223771B2
公开(公告)日:2007-05-29
申请号:US10485515
申请日:2002-07-31
申请人: Wilm Buhr , Jörg Senn-Bilfinger
发明人: Wilm Buhr , Jörg Senn-Bilfinger
IPC分类号: C07D221/06 , A61K31/437
CPC分类号: C07D491/14
摘要: The invention provides compounds of the formula (I), in which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid.
摘要翻译: 本发明提供式(I)化合物,其中取代基和符号如说明书中所定义。 这些化合物抑制胃酸的分泌。
-
公开(公告)号:US06916825B2
公开(公告)日:2005-07-12
申请号:US10240039
申请日:2001-03-28
申请人: Jörg Senn-Bilfinger , Wilm Buhr
发明人: Jörg Senn-Bilfinger , Wilm Buhr
IPC分类号: C07D491/147 , A61K31/415 , A61K31/435 , A61K31/437 , A61K31/4375 , A61P1/04 , C07D471/14 , C07D491/14 , A01N43/42
CPC分类号: C07D471/14 , C07D491/14
摘要: Compounds of the formula 1 in which the substituents have the meanings mentioned in the description are suitable for the prevention and treatment of gastrointestinal diseases.
摘要翻译: 其中取代基具有本说明书中提及的含义的式1化合物适用于预防和治疗胃肠道疾病。
-
公开(公告)号:US06716990B2
公开(公告)日:2004-04-06
申请号:US10149290
申请日:2002-06-11
IPC分类号: C07D23504
CPC分类号: C07D405/06 , C07D233/90
摘要: The invention relates to compounds of formula (2) in which R1, R2, R3 and R4 have the meanings indicated in the description, their preparation and their further reaction to give compounds of formula (1), in which A1, A2 and R4 have the meanings indicated in the description. The compounds of the formula (1) are valuable intermediates for the preparation of medicaments.
摘要翻译: 本发明涉及式(2)化合物,其中R 1,R 2,R 3和R 4具有说明书中所述的含义及其制备方法及其进一步的反应,得到式(1)化合物,其中A 1,A 2和R 4具有 说明中指出的含义。 式(1)的化合物是用于制备药物的有价值的中间体。
-
公开(公告)号:US07393860B1
公开(公告)日:2008-07-01
申请号:US11493707
申请日:2006-07-27
申请人: Jörg Senn-Bilfinger
发明人: Jörg Senn-Bilfinger
IPC分类号: A61K31/437 , A61K31/4375 , C07D471/12 , C07D471/14
CPC分类号: C07D471/14
摘要: The compound (7R,8R,9R)-2,3-Dimethyl-8-hydroxy-7-(2-methoxyethoxy)-9-phenyl-7,8,9,10-tetrahydro-imidazo-[1,2-h] [1,7] naphthyridine inhibits the secretion of gastric acid.
摘要翻译: 化合物(7R,8R,9R)-2,3-二甲基-8-羟基-7-(2-甲氧基乙氧基)-9-苯基-7,8,9,10-四氢 - 咪唑并[1,2-h ] [1,7]萘啶抑制胃酸的分泌。
-
-
-
-
-
-
-
-
-