公开(公告)号：US20240336629A1

公开(公告)日：2024-10-10

申请号：US18276269

申请日：2022-01-26

Applicant: JACOBIO PHARMACEUTICALS CO., LTD.

Inventor： Haijun LI ,  Mingming CHEN ,  Di KANG ,  Qinglong LI ,  Lei ZHANG ,  Man YAN ,  Wei LONG ,  Yanping WANG ,  Hao ZHANG ,  Cunbo MA ,  Amin LI

IPC: C07D513/14 ,  C07D471/14 ,  C07D498/14 ,  C12N9/99

CPC classification number: C07D513/14 ,  C07D471/14 ,  C07D498/14 ,  C12N9/99

Abstract: Provided are a compound of formula (I) that inhibit the activity of PARP7, a stereoisomer thereof, a deuterated derivative thereof, or a pharmaceutically acceptable salt thereof, an intermediate to prepare the compound, a process to prepare the compound, a composition comprising the same, and the methods of using the same.