公开(公告)号：US11597746B2

公开(公告)日：2023-03-07

申请号：US17260886

申请日：2019-07-16

Applicant: JANSSEN BIOTECH, INC.

Inventor： Stuart Emanuel ,  Mark Richter ,  Peter J. Connolly ,  James P. Edwards ,  Guangyi Wang ,  Santhosh Kumar Thatikonda ,  Leonid Beigelman ,  Gilles Bignan ,  Wim Bert Griet Schepens ,  Marcel Viellevoye ,  Johannes Wilhelmus J. F. Thuring

IPC: C07H19/207 ,  C07H19/23 ,  A61P35/00

Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I), wherein R1, R1′, X1, B1, R2, R2′, B2, X2, R3, Z-M-Y, and Y1-M1-Z1 are as defined herein.

公开(公告)号：US20230287034A1

公开(公告)日：2023-09-14

申请号：US18177864

申请日：2023-03-03

Applicant: JANSSEN BIOTECH, INC.

Inventor： Stuart Emanuel ,  Mark Richter ,  Peter J. Connolly ,  James P. Edwards ,  Guangyi Wang ,  Santhosh Kumar Thatikonda ,  Leonid Beigelman ,  Gilles Bignan ,  Wim Bert Griet Schepens ,  Marcel Viellevoye ,  Johannes Wilhelmus J.F. Thuring

IPC: C07H19/207 ,  A61P35/00 ,  C07H19/23

CPC classification number: C07H19/207 ,  A61P35/00 ,  C07H19/23

Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as follows:




wherein R1, R1′, X1, B1, R2, R2′, B2, X2, R3, Z-M-Y, and Y1-M1-Z1 are as defined herein.

公开(公告)号：US20210277046A1

公开(公告)日：2021-09-09

申请号：US17260886

申请日：2019-07-16

Applicant: JANSSEN BIOTECH, INC.

Inventor： Stuart Emanuel ,  Mark Richter ,  Peter J. Connolly ,  James P. Edwards ,  Guangyi Wang ,  Santhosh Kumar Thatikonda ,  Leonid Beigelman ,  Gilles Bignan ,  Wim Bert Griet Schepens ,  Marcel Viellevoye ,  Johannes Wilhelmus J.F. Thuring

IPC: C07H19/207 ,  A61P35/00 ,  C07H19/23

Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I), wherein R1, R1′, X1, B1, R2, R2′, B2, X2, R3, Z-M-Y, and Y1-M1-Z1 are as defined herein.