公开(公告)号：US12134658B2

公开(公告)日：2024-11-05

申请号：US17391744

申请日：2021-08-02

Applicant: JANSSEN BIOTECH, INC.

Inventor： Rajkumar Ganesan ,  Adam Zwolak ,  Ian White ,  Ninkka Tamot ,  Paul B. Harvilla ,  Rajitha Doddareddy ,  Sanjaya Singh ,  Martin Jack Borrok, III

IPC: C07K16/40 ,  A61K39/00 ,  C07K16/10 ,  C07K16/28

Abstract: Provided herein are multispecific molecules comprising a first binding domain that specifically binds to polymeric immunoglobulin receptor (pIgR) and a second binding domain that specifically binds to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related methods for the treatment of patients infected with SARS-CoV-2.