公开(公告)号：US20230143550A1

公开(公告)日：2023-05-11

申请号：US17689869

申请日：2022-03-08

Applicant: JANSSEN BIOTECH, INC.

Inventor： Rebecca HAWKINS ,  Steven JACOBS ,  Manuel SEPULVEDA

IPC: C07K14/78 ,  G01N33/569 ,  G01N33/68 ,  G01N33/566 ,  A61K51/08 ,  G01N33/53 ,  A61K49/00 ,  G01N33/574

CPC classification number: C07K14/78 ,  G01N33/56966 ,  G01N33/6887 ,  G01N33/566 ,  A61K51/088 ,  G01N33/53 ,  A61K49/0002 ,  G01N33/68 ,  G01N33/569 ,  G01N33/57492 ,  G01N33/574 ,  G01N2333/70517 ,  G01N2333/78

Abstract: Fibronectin type III domains (FN3) that specifically bind to CD8A, related polynucleotides capable of encoding CD8A-specific FN3 domains, cells expressing the FN3 domains, as well as associated vectors, and detectably labeled FN3 domains are useful in therapeutic and diagnostic applications.