公开(公告)号：US20240173309A1

公开(公告)日：2024-05-30

申请号：US18495457

申请日：2023-10-26

申请人： JANSSEN BIOTECH, INC. ,  PROTAGONIST THERAPEUTICS, INC.

发明人： Santhosh NEELAMKAVIL ,  Chengzao SUN ,  Sandeep SOMANI ,  Stephanie A. BARROS ,  Raymond J. PATCH ,  Jing ZHANG ,  Douglas RIEXINGER ,  Charles HENDRICK ,  Elisabetta BIANCHI ,  Roberto COSTANTE ,  Federica ROSOLIA ,  Martina LOLLOBRIGIDA ,  Sonia DEL RIZZO ,  Danila BRANCA ,  Ashok BHANDARI ,  James DANIEL ,  Tran Trung TRAN ,  Brian FREDERICK

IPC分类号： A61K31/4439 ,  A61P37/02

CPC分类号： A61K31/4439 ,  A61P37/02

摘要： The present invention relates to novel lipidated peptide inhibitors of the interleukin-23 receptor (IL-23R) or pharmaceutically acceptable salts, solvates and/or other forms thereof, corresponding pharmaceutical compositions, methods and/or uses of the IL-23R inhibitors for treatment of autoimmune inflammation diseases and/or related disorders.