公开(公告)号：US20230365934A1

公开(公告)日：2023-11-16

申请号：US18027892

申请日：2021-09-22

申请人： JBM Incorporation ,  Mebiol Inc. ,  GN Incorporation Co Ltd

发明人： Shojiro KATOH ,  Hiroshi YOSHIOKA ,  Samuel JK ABRAHAM

IPC分类号： C12N5/077

CPC分类号： C12N5/0655 ,  C12N2533/30

摘要： A first method is provided for increasing the tissue regeneration capacity of a cell population, a cell population production method that includes the first method, and a cell population produced using the production method. The methods for increasing the tissue regeneration capacity of a cell population can include, for example, a step for incubating a cell population in a gel-like thermoreversible polymer solution.

公开(公告)号：US20200330375A1

公开(公告)日：2020-10-22

申请号：US16753592

申请日：2018-10-01

申请人： GN Corporation Ltd. ,  JBM Incorporation

发明人： Hiroshi YOSHIOKA ,  Samuel Abraham J.K.

IPC分类号： A61K9/00 ,  A61K9/06 ,  A61K35/38 ,  A61P13/02

摘要： [Object]The present invention is intended to provide a urethral stricture treatment agent and a urethral stricture treatment method capable of avoiding restenosis by a less invasive transurethral endoscopic procedure in urethral stricture treatment.[Solution]A urethral stricture treatment agent including at least a hydrogel-forming polymer, and having a storage elastic modulus of 50 Pa or less at 10° C. and a storage elastic modulus of 100 Pa or more at 37° C.A urethral stricture treatment method at least including injecting the urethral stricture treatment agent cooled to 10° C. or lower into an inner surface of urethra which has been incised with a transurethral endoscopic procedure, and holding the urethral stricture treatment agent in the inner surface of urethra at a temperature not lower than a room temperature.

公开(公告)号：US20200260671A1

公开(公告)日：2020-08-20

申请号：US16852055

申请日：2020-04-17

申请人： MEBIOL INC.

发明人： Hiroshi YOSHIOKA ,  Yuichi MORI ,  Akihiro OKAMOTO ,  Shigeki MIURA ,  Tomoyoshi MIZUTANI

IPC分类号： A01G31/02 ,  A01G25/02 ,  A01G31/00

摘要： Prior art technology has a problem in that when a plant is cultivated for a long period of time on a PVA film having its lower surface positioned in contact with a nutrient fluid, plant roots that have formed penetrate through the film. A plant cultivation system wherein the PVA film has an equilibrium degree of swelling in the range of from 125 to 250% as measured in water at 30° C. and has a loss tangent (tan δ) in the range of from 0.005 to 0.2 as measured in an equilibrium swollen state in water at 30° C., and a method for cultivating a plant by using this plant cultivation system. Plant cultivation can be performed for a long period of time while avoiding infection by bacteria and the like causative of plant diseases. Therefore, the present invention is useful in, e.g., agriculture and the manufacture of pharmaceuticals.