公开(公告)号：US20210246138A1

公开(公告)日：2021-08-12

申请号：US17264670

申请日：2019-07-31

Applicant: JOINT STOCK COMPANY "BIOCAD"

Inventor： Aleksei Leonidovich MINDICH ,  Anna Jur'evna CHESTNOVA ,  Mariia Andreevna KASATKINA ,  Andrei Ivanovich ALAFINOV ,  Aleksei Sergeevich GAVRILOV ,  Anton Aleksandrovich EVDOKIMOV ,  Liliana Vyacheslavovna LENSHMIDT ,  Elena Aleksandrovna MAKSIMENKO ,  Mariia Sergeevna MISHINA ,  Sergei Aleksandrovich SILONOV ,  Evgenii Jur'evich SMIRNOV ,  Pavel Andreevich IAKOVLEV ,  Dmitry Valentinovich MOROZOV

IPC: C07D471/04 ,  A61P35/00

Abstract: The present invention relates to novel compounds of formula I: which have the properties of CDK8/19 inhibitors, to a pharmaceutical composition comprising said compounds, and to use thereof as a medicine for treating diseases and disorders.