公开(公告)号：US11840531B2

公开(公告)日：2023-12-12

申请号：US17264670

申请日：2019-07-31

Applicant: JOINT STOCK COMPANY “BIOCAD”

Inventor： Aleksei Leonidovich Mindich ,  Anna Jur'evna Chestnova ,  Mariia Andreevna Kasatkina ,  Andrei Ivanovich Alafinov ,  Aleksei Sergeevich Gavrilov ,  Anton Aleksandrovich Evdokimov ,  Liliana Vyacheslavovna Lenshmidt ,  Elena Aleksandrovna Maksimenko ,  Mariia Sergeevna Mishina ,  Sergei Aleksandrovich Silonov ,  Evgenii Jur'evich Smirnov ,  Pavel Andreevich Iakovlev ,  Dmitry Valentinovich Morozov

IPC: C07D471/04 ,  A61P35/00 ,  A61K31/4375

CPC classification number: C07D471/04 ,  A61K31/4375 ,  A61P35/00

Abstract: The present invention relates to novel compounds of formula I:




which have the properties of CDK8/19 inhibitors, to a pharmaceutical composition comprising said compounds, and to use thereof as a medicine for treating diseases and disorders.