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公开(公告)号：US07867705B2
公开(公告)日：2011-01-11
申请号：US11575627
申请日：2005-01-05
CPC分类号： C07K14/82 , A01K67/0275 , A01K2217/052 , A01K2217/15 , A01K2227/105 , A01K2267/0331 , A61K38/179 , C07K16/28 , C07K2317/34 , C12N2710/22022 , C12N2730/10122 , G01N33/5067 , G01N33/57438 , G01N2500/00
摘要： The present specification provides, inter alia, methods of using Wnt and FZD proteins, genes, FZD and Wnt-specific antibodies and probes in diagnosis and treatment of cancer and for screening test compounds for an ability to treat cancer. Also disclosed are compounds useful for treating cancer such as liver cancer.
摘要翻译： 本说明书尤其提供了在癌症诊断和治疗中使用Wnt和FZD蛋白，基因，FZD和Wnt特异性抗体和探针并用于筛选测试化合物以治疗癌症的方法。 还公开了可用于治疗癌症如肝癌的化合物。
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公开(公告)号：US20080194457A1
公开(公告)日：2008-08-14
申请号：US11575627
申请日：2005-01-05
IPC分类号： A61K38/00 , C12Q1/68 , G01N33/574 , A01K67/027 , A61P1/00 , G01N33/566 , C12N5/06 , A61K31/70
CPC分类号： C07K14/82 , A01K67/0275 , A01K2217/052 , A01K2217/15 , A01K2227/105 , A01K2267/0331 , A61K38/179 , C07K16/28 , C07K2317/34 , C12N2710/22022 , C12N2730/10122 , G01N33/5067 , G01N33/57438 , G01N2500/00
摘要： The present specification provides, inter alia, methods of using Wnt and FZD proteins, genes, FZD and Wnt-specific antibodies and probes in diagnosis and treatment of cancer and for screening test compounds for an ability to treat cancer. Also disclosed are compounds useful for treating cancer such as liver cancer.
摘要翻译： 本说明书尤其提供了在癌症诊断和治疗中使用Wnt和FZD蛋白，基因，FZD和Wnt特异性抗体和探针并用于筛选测试化合物以治疗癌症的方法。 还公开了可用于治疗癌症如肝癌的化合物。
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公开(公告)号：US20090036568A1
公开(公告)日：2009-02-05
申请号：US11873950
申请日：2007-10-17
IPC分类号： C08K7/02 , C08F283/06 , B01J13/18 , H04B7/185
CPC分类号： B01J13/18
摘要： A self-healing material comprises a matrix embedded with micro-pockets of a healing-agent releasable by a crack in the matrix. The healing-agent is able to bond to the matrix to repair the crack. The healing-agent is contained in microcapsules. A corresponding catalyst for the healing-agent is embedded in the matrix and contained in a plurality of microcapsules as an emulsion. The emulsion comprises an oil, a perfluorated solvent, a hydrophobic ionic liquid, or mixtures thereof. A method of manufacturing the self-healing material comprises the steps of identifying an operational temperature range of the material, providing at least one substance as the healing-agent, which substance remaining substantially in a liquid state within the operational temperature range, identifying an operational evaporation rate of the healing-agent and providing the substance with a curing time according to the evaporation rate.
摘要翻译： 自修复材料包括嵌入有由基质中的裂纹释放的愈合剂的微穴的基质。 愈合剂能够与基体结合以修复裂纹。 愈合剂包含在微胶囊中。 用于愈合剂的相应催化剂被包埋在基质中并且作为乳液包含在多个微胶囊中。 该乳液包含油，全氟化溶剂，疏水性离子液体或其混合物。 制造自修复材料的方法包括以下步骤：鉴定材料的工作温度范围，提供至少一种物质作为愈合剂，该物质在工作温度范围内基本保持在液态，识别操作 愈合剂的蒸发速率，并根据蒸发速率为物质提供固化时间。
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4.发明授权Adaptation of service applications to heterogeneous execution context by means of smart cards 失效通过智能卡适应服务应用程序到异构执行上下文公开(公告)号：US06862614B2
公开(公告)日：2005-03-01
申请号：US09785321
申请日：2001-02-20
申请人： Pierre Paradinas , Jean-Jacques Vandewalle , Christophe Muller , Philippe Merle , Christophe Gransart , Jean-Marc Geib
发明人： Pierre Paradinas , Jean-Jacques Vandewalle , Christophe Muller , Philippe Merle , Christophe Gransart , Jean-Marc Geib
IPC分类号： G07F7/10 , G06F15/177
CPC分类号： G07F7/1008 , G06Q20/341 , G06Q20/3552 , G06Q20/357
摘要： Service applications are provided on multiple types of devices with different execution contexts. A smart card stores the application description, and processes it to install an adapted configuration of the application for whatever device it is inserted in. Smart cards are compatible with many devices, as well as being small, resistant, and tamper-proof. In addition to security features, their processing capacities can be used to at least partially treat the abstract descriptions of the applications in order to produce concrete descriptions adapted to the execution context.
摘要翻译： 服务应用程序在具有不同执行上下文的多种类型的设备上提供。 智能卡存储应用程序描述，并处理它以安装其插入的任何设备的应用程序的适配配置。智能卡与许多设备兼容，以及小巧，耐用和防篡改。 除了安全特征之外，它们的处理能力可用于至少部分地对应用的抽象描述进行处理，以便产生适应于执行上下文的具体描述。
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公开(公告)号：US08990835B2
公开(公告)日：2015-03-24
申请号：US13554973
申请日：2012-07-20
摘要： A data distribution system based on the exchange of asynchronous messages in publication/subscription mode, for the exchange of data according to various qualities of service between a transmitter running a data supplying application and one receiver running a data receiving application is disclosed, which transmitter and receiver are interconnected by a communication network, via communication objects. Communication objects provide one programming interface to exchange messages. In one aspect, a communication object is broken down into a number of components comprising a type-1 component comprising the programming interface, and at least one type-2 component adapted to control information related to the type-1 component and providing the operations responsible for functionalities reconfigurable during runtime, which communication object has a mechanism for providing runtime reconfiguration requests to the at least one type-2 component, so as to allow for the reconfiguration during runtime of a functionality associated with the communication object.
摘要翻译： 公开了一种基于在出版/订阅模式下交换异步消息的数据分发系统，用于根据运行数据提供应用的发射机的运营商和运行数据接收应用的一个接收机之间的各种服务质量交换数据，哪个发射机和 接收机通过通信网络通过通信对象互连。 通信对象提供一个编程接口来交换消息。 在一个方面，通信对象被分解为包括包括编程接口的类型1组件的多个组件，以及适于控制与类型1组件有关的信息并提供负责的操作的至少一个类型2组件 对于在运行时期间可重新配置的功能，该通信对象具有用于向至少一个类型2组件提供运行时重新配置请求的机制，以便允许在与通信对象相关联的功能的运行时期间重新配置。
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公开(公告)号：US08865798B2
公开(公告)日：2014-10-21
申请号：US11873950
申请日：2007-10-17
IPC分类号： C08K9/00
CPC分类号： B01J13/18
摘要： A self-healing material comprises a matrix embedded with micro-pockets of a healing-agent releasable by a crack in the matrix. The healing-agent is able to bond to the matrix to repair the crack. The healing-agent is contained in microcapsules. A corresponding catalyst for the healing-agent is embedded in the matrix and contained in a plurality of microcapsules as an emulsion. The emulsion comprises an oil, a perfluorated solvent, a hydrophobic ionic liquid, or mixtures thereof. A method of manufacturing the self-healing material comprises the steps of identifying an operational temperature range of the material, providing at least one substance as the healing-agent, which substance remaining substantially in a liquid state within the operational temperature range, identifying an operational evaporation rate of the healing-agent and providing the substance with a curing time according to the evaporation rate.
摘要翻译： 自修复材料包括嵌入有由基质中的裂纹释放的愈合剂的微穴的基质。 愈合剂能够与基体结合以修复裂纹。 愈合剂包含在微胶囊中。 用于愈合剂的相应催化剂被包埋在基质中并且作为乳液包含在多个微胶囊中。 乳液包含油，全氟化溶剂，疏水性离子液体或其混合物。 制造自修复材料的方法包括以下步骤：鉴定材料的工作温度范围，提供至少一种物质作为愈合剂，该物质在工作温度范围内基本保持在液态，识别操作 愈合剂的蒸发速率，并根据蒸发速率为物质提供固化时间。
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公开(公告)号：US20130024874A1
公开(公告)日：2013-01-24
申请号：US13554973
申请日：2012-07-20
摘要： A data distribution system based on the exchange of asynchronous messages in publication/subscription mode, for the exchange of data according to various qualities of service between a transmitter running a data supplying application and one receiver running a data receiving application is disclosed, which transmitter and receiver are interconnected by a communication network, via communication objects. Communication objects provide one programming interface to exchange messages. In one aspect, a communication object is broken down into a number of components comprising a type-1 component comprising the programming interface, and at least one type-2 component adapted to control information related to the type-1 component and providing the operations responsible for functionalities reconfigurable during runtime, which communication object has a mechanism for providing runtime reconfiguration requests to the at least one type-2 component, so as to allow for the reconfiguration during runtime of a functionality associated with the communication object.
摘要翻译： 公开了一种基于在出版/订阅模式下交换异步消息的数据分发系统，用于根据运行数据提供应用的发射机的运营商和运行数据接收应用的一个接收机之间的各种服务质量交换数据，哪个发射机和 接收机通过通信网络通过通信对象互连。 通信对象提供一个编程接口来交换消息。 在一个方面，通信对象被分解为包括包括编程接口的类型1组件的多个组件，以及适于控制与类型1组件有关的信息并提供负责的操作的至少一个类型2组件 对于在运行时期间可重新配置的功能，该通信对象具有用于向至少一个类型2组件提供运行时重新配置请求的机制，以便允许在与通信对象相关联的功能的运行时期间重新配置。
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