专利检索 ap:("James A. Monn" OR "Andrew Thurkauf" OR "Shunichi Yamaguchi" OR "Michael A. Rogawski" OR "Kenner C. Rice" OR "Mariena V. Mattson" OR "Arthur E. Jacobson") AND inv:"Michael A. Rogawski" 第 1 页

1.

发明授权
5-aminocarbonyl-5H-dibenzo[a.d]cyclohepten-5,10-imines for treatment of epilepsy and cocaine addiction 失效
标题翻译：用于治疗癫痫和可卡因成瘾的5-氨基羰基-5H-二苯并[a.d]环庚烯-5,10-亚胺

公开(公告)号：US5196415A

公开(公告)日：1993-03-23

申请号：US827383

申请日：1992-01-29

申请人： James A. Monn , Andrew Thurkauf , Shunichi Yamaguchi , Michael A. Rogawski , Kenner C. Rice , Mariena V. Mattson , Arthur E. Jacobson

发明人： James A. Monn , Andrew Thurkauf , Shunichi Yamaguchi , Michael A. Rogawski , Kenner C. Rice , Mariena V. Mattson , Arthur E. Jacobson

IPC分类号： C07D451/02 , C07D471/20

CPC分类号： C07D451/00

摘要： This invention is in the field of clinical neurology and relates specifically to compounds, compositions and methods for treatment of patients with generalized epilepsy or partial (symptomatic) epilepsy using compounds of the formula: ##STR1## This invention also relates to compounds, compositions and methods of treatment for drug craving in patients addicted to cocaine.

摘要翻译： 本发明在临床神经学领域中，具体涉及用下列化合物治疗广泛性癫痫患者或部分（症状性）癫痫患者的化合物，组合物和方法：本发明还涉及化合物，组合物和方法对可卡因成瘾患者的药物渴求的治疗。

2.

发明申请
INTRAPULMONARY BENZODIAZEPINE FOR THE TREATMENT AND PREVENTION OF SEIZURES 审中-公开
标题翻译：用于治疗和预防癫痫的泌尿生殖道感染

公开(公告)号：US20130309306A1

公开(公告)日：2013-11-21

申请号：US13885660

申请日：2011-12-01

申请人： Michael A. Rogawski , Ashish Dhir

发明人： Michael A. Rogawski , Ashish Dhir

IPC分类号： A61K9/00 , A61K31/5517

CPC分类号： A61K9/007 , A61K31/55 , A61K31/5513 , A61K31/5517

摘要： This invention provides methods for the amelioration, termination and/or abortion of a seizure by the intrapulmonary administration of a benzodiazepine, for example, midazolam.

摘要翻译： 本发明提供了通过肺内施用苯二氮卓类，例如咪达唑仑来改善，终止和/或流产癫痫发作的方法。

3.

发明授权
Androstane and pregnane steroids with potent allosteric GABA receptor chloride ionophore modulating properties 有权
标题翻译：具有强效变构GABA受体氯离子载体调节性质的雄甾烷和孕甾类固醇

公开(公告)号：US08575375B2

公开(公告)日：2013-11-05

申请号：US12664470

申请日：2008-06-16

申请人： Scott P. Runyon , Michael A. Rogawski , John Kepler , Hernan Navarro , Rafal Kaminski , Matthew Orr , Kevin M. Cook

发明人： Scott P. Runyon , Michael A. Rogawski , Edgar Cook , John Kepler , Hernan Navarro , Rafal Kaminski , Matthew Orr

IPC分类号： C07J41/00

CPC分类号： C07J41/0005 , C07J7/00 , C07J31/003

摘要： This invention describes compounds of Structures 1, 2, and 3 and their use as allosteric modulators of the GABA receptor chloride ionophore complex to alleviate stress, anxiety, mood disorders, seizures, depression, treatment of drug and alcohol abuse, memory, premenstrual disorders, and neural system damage.

摘要翻译： 本发明描述了结构1,2和3的化合物及其作为GABA受体氯离子载体复合物的变构调节剂的用途，以缓解压力，焦虑，情绪障碍，癫痫发作，抑郁症，药物和酒精滥用的治疗，记忆，经前期障碍，和神经系统损伤。