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公开(公告)号：US4911233A
公开(公告)日：1990-03-27
申请号：US234582
申请日：1988-08-22
申请人： James C. Chao , Tzer-Fen Chen
发明人： James C. Chao , Tzer-Fen Chen
CPC分类号： B01D5/0027 , F28B3/02 , Y10S165/162 , Y10S165/907 , Y10S165/913
摘要： A process for condensing vapor or mist material onto a thin first liquid film surface, which liquid film is generated and supported on the outer surface of a porous structure. A moving condensable vapor contacts the thin liquid film and is condensed onto the liquid surface. The condensed vapor drains by gravity action into a collection zone, together with a portion of the liquid film material being entrained therein. The vapor or mist material can be either substantially immiscible or miscible in the liquid film. The first liquid is preferably provided in a closed system and is recycled at near ambient temperature and at pressure conditions sufficient to produce the thin liquid film external to the porous structure, which has a porosity of 20-80%. An apparatus including the porous structure and liquid handling system for condensing an upflowing condensable vapor is disclosed.
摘要翻译： 一种用于将蒸气或雾材料冷凝到薄的第一液膜表面上的方法，该薄膜在多孔结构的外表面上产生和支撑。 移动的可冷凝蒸汽接触薄液膜并冷凝到液体表面上。 冷凝的蒸汽通过重力作用排入收集区，一部分液膜材料被夹带在其中。 蒸气或烟雾材料可以与液膜基本上是不混溶的或可混溶的。 第一液体优选地设置在封闭系统中，并且在接近环境温度和足以产生孔隙率为20-80％的多孔结构外部的薄液体膜的压力条件下再循环。 公开了一种包括用于冷凝可向上流动的可冷凝蒸气的多孔结构和液体处理系统的装置。
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公开(公告)号：US07914979B2
公开(公告)日：2011-03-29
申请号：US11718348
申请日：2005-11-04
IPC分类号： C12Q1/70
CPC分类号： A61K9/0019 , A61K47/26 , C12N7/00 , C12N2760/18151
摘要： Envelope viruses (e.g. Newcastle disease virus (NDV)) are formulated for storage at moderately cold temperatures (e.g. −20° C.). The formulation is an aqueous solution containing the enveloped virus at a concentration of from 106 PFU/mL to 1012 PFU/mL; and a non-reducing saccharide (e.g. sucrose). When the non-reducing saccharide is a disaccharide it is present in the solution at a concentration of from 5% (w/v) to 50% (w/v), and when it is a monosaccharide it is present in the solution at a concentration of from 2.5% (w/v) to 25% (w/v). The solution has an osmotic pressure of about 250 mOs or higher, and has a pH of from 5 to 10.
摘要翻译： 包膜病毒（例如新城疫病毒（NDV））被配制用于在适度的低温（例如-20℃）下储存。 该制剂是含有浓度为106PFU / mL至1012PFU / mL的包膜病毒的水溶液; 和非还原性糖（例如蔗糖）。 当非还原性糖是二糖时，以5％（w / v）至50％（w / v）的浓度存在于溶液中，当其为单糖时，其存在于溶液中 浓度为2.5％（w / v）至25％（w / v）。 溶液的渗透压为约250mOs以上，pH为5〜10。
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公开(公告)号：US20080166784A1
公开(公告)日：2008-07-10
申请号：US11718348
申请日：2005-11-04
IPC分类号： C12N7/00
CPC分类号： A61K9/0019 , A61K47/26 , C12N7/00 , C12N2760/18151
摘要： Envelope viruses (e.g. Newcastle disease virus (NDV)) are formulated for storage at moderately cold temperatures (e.g. −20 C). The formulation is an aqueous solution containing the enveloped virus at a concentration of from 106 PFU/mL to 1012 PFU/mL; and a non-reducing saccharide (e.g. sucrose). When the non-reducing saccharide is a disaccharide it is present in the solution at a concentration of from 5% (w/v) to 50% (w/v), and when it is a monosaccharide it is present in the solution at a concentration of from 2.5% (w/v) to 25% (w/v). The solution has an osmotic pressure of about 250 mOs or higher, and has a pH of from 5 to 10.
摘要翻译： 包膜病毒（例如新城疫病毒（NDV））被配制用于在适度的低温（例如-20℃）下储存。 制剂是含有浓度为10 -6 PFU / mL至10 12 PFU / mL的包膜病毒的水溶液; 和非还原性糖（例如蔗糖）。 当非还原性糖是二糖时，以5％（w / v）至50％（w / v）的浓度存在于溶液中，当其为单糖时，其存在于溶液中 浓度为2.5％（w / v）至25％（w / v）。 溶液的渗透压为约250mOs以上，pH为5〜10。
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公开(公告)号：US20060008498A1
公开(公告)日：2006-01-12
申请号：US10889615
申请日：2004-07-12
申请人： Tzer-Fen Chen
发明人： Tzer-Fen Chen
CPC分类号： A61K9/145 , A61K9/0019
摘要： Larger particles (e.g., larger than 100 μm) of a material are processed to generate smaller particles having dimensions smaller than 200 nm. At least a portion of the processing is performed under a cryogenic condition and based on at least a physical property of the material under the cryogenic condition.
摘要翻译： 处理较大颗粒（例如，大于100μm）的材料以产生尺寸小于200nm的较小颗粒。 处理的至少一部分在低温条件下进行，并且至少基于在低温条件下材料的物理性质。
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