公开(公告)号：US20190194279A1

公开(公告)日：2019-06-27

申请号：US16329800

申请日：2017-09-04

Applicant: James Cook University

Inventor： Alex Loukas ,  Michael Smout ,  Norelle Daly

IPC: C07K14/475 ,  A61P17/02

CPC classification number: C07K14/475 ,  A61K38/00 ,  A61P17/02 ,  A61P43/00

Abstract: Peptides derived from the N-terminal region of granulin have activity in promoting cell proliferation, migration and/or wound healing. Furthermore, an additional disulphide bond may be engineered into such peptides to improve or otherwise modify the folding of the peptide. The peptides may also be modified such as at proline residues improve the ability of the peptide to promote cell proliferation.