公开(公告)号：US20120077285A1

公开(公告)日：2012-03-29

申请号：US13257188

申请日：2010-03-25

Applicant: Janina Cramer

Inventor： Janina Cramer

IPC: G01N33/53 ,  C07H1/08 ,  H01F1/00 ,  C07K1/14 ,  C07H3/00 ,  B01D11/02 ,  C07H21/04 ,  C07K14/00

CPC classification number: G01N33/54326 ,  B03C1/00 ,  B03C2201/18 ,  C12N15/1013

Abstract: The present invention relates to a method for purifying biomolecules or for analyzing whether an aqueous phase contains biomolecules by means of magnetic separation. The invention further relates to uses, to devices, and to kits that relate to the method according to the invention.

Abstract translation: 本发明涉及一种纯化生物分子的方法或用于分析水相是否含有通过磁选分离的生物分子。 本发明还涉及与根据本发明的方法相关的用途，装置和套件。

公开(公告)号：US09518983B2

公开(公告)日：2016-12-13

申请号：US13257188

申请日：2010-03-25

Applicant: Janina Cramer

Inventor： Janina Cramer

IPC: G01N33/543 ,  B03C1/00 ,  C12N15/10

CPC classification number: G01N33/54326 ,  B03C1/00 ,  B03C2201/18 ,  C12N15/1013

Abstract: The present invention relates to a method for purifying biomolecules or for analyzing whether an aqueous phase contains biomolecules by means of magnetic separation. The invention further relates to uses, to devices, and to kits that relate to the method according to the invention.

Abstract translation: 本发明涉及一种纯化生物分子的方法或用于分析水相是否含有通过磁选分离的生物分子。 本发明还涉及与根据本发明的方法相关的用途，装置和套件。

公开(公告)号：US20110008846A1

公开(公告)日：2011-01-13

申请号：US12810714

申请日：2008-12-12

Applicant: Lars-Erik Peters ,  Nan Fang ,  Janina Cramer

Inventor： Lars-Erik Peters ,  Nan Fang ,  Janina Cramer

IPC: C12P19/34 ,  C12N9/96

CPC classification number: C12N9/2497 ,  C12N9/1252

Abstract: The invention relates to an active enzyme of bacterial, fungal, viral, or archae origin, wherein the enzyme is coupled, preferably covalently coupled with at least one polymer having a molecular weight between about 500 to about 20,000 daltons selected from the group consisting of polyethylene glycol and polypropylene glycol. The invention relates in particular to uses thereof of such as in molecular biology as well as kits comprising such enzymes. In preferred embodiments the enzymes of the invention are nucleic acid modifying or replicating enzymes.

Abstract translation: 本发明涉及细菌，真菌，病毒或古菌来源的活性酶，其中该酶被偶联，优选与至少一种分子量为约500至约20,000道尔顿的聚合物共价偶联，所述聚合物选自聚乙烯 乙二醇和聚丙二醇。 本发明特别涉及其在分子生物学中的用途以及包含这些酶的试剂盒。 在优选的实施方案中，本发明的酶是核酸修饰或复制酶。