公开(公告)号：US20220062415A1

公开(公告)日：2022-03-03

申请号：US17524516

申请日：2021-11-11

Applicant: Janssen Biotech, Inc.

Inventor： Hong Xie ,  Andrew Cakana

IPC: A61K39/395 ,  A61K31/198 ,  A61K31/573 ,  C07K16/28 ,  A61K9/00 ,  A61K47/12 ,  A61K47/02 ,  A61K47/26 ,  A61K47/42 ,  A61K47/22 ,  A61K47/20 ,  A61P35/00 ,  A61K31/69 ,  G06Q30/00 ,  G06Q30/06 ,  G06Q30/02

Abstract: Described herein are methods of treating multiple myeloma with clinically proven safe and effective amounts of an antibody that specifically recognizes CD38 with bortezomib, melphalan, and prednisone. Also described are methods of selling or offering for sale an antibody that specifically recognizes CD38 or pharmaceutical compositions thereof with bortezomib, melphalan, and prednisone.

公开(公告)号：US20190298827A1

公开(公告)日：2019-10-03

申请号：US16374031

申请日：2019-04-03

Applicant: Janssen Biotech, Inc.

Inventor： Hong Xie ,  Andrew Cakana

IPC: A61K39/395 ,  A61K31/69 ,  A61K31/198 ,  A61K31/573 ,  C07K16/28 ,  A61K9/00 ,  A61K47/12 ,  A61K47/02 ,  A61K47/26 ,  A61K47/42 ,  A61K47/22 ,  A61K47/20 ,  A61P35/00

Abstract: Described herein are methods of treating multiple myeloma with clinically proven safe and effective amounts of an antibody that specifically recognizes CD38 with bortezomib, melphalan, and prednisone. Also described are methods of selling or offering for sale an antibody that specifically recognizes CD38 or pharmaceutical compositions thereof with bortezomib, melphalan, and prednisone.

公开(公告)号：US11591395B2

公开(公告)日：2023-02-28

申请号：US16852353

申请日：2020-04-17

Applicant: Janssen Biotech, Inc.

Inventor： Theresa McDevitt ,  Shoba Shetty ,  Hong Xie

IPC: C07K16/28 ,  A61P35/04 ,  A61K9/00 ,  C07K16/30 ,  A61K45/06

Abstract: Bispecific monoclonal antibodies and methods for treating cancer are set forth herein.

公开(公告)号：US20210040209A1

公开(公告)日：2021-02-11

申请号：US16852353

申请日：2020-04-17

Applicant: Janssen Biotech, Inc.

Inventor： Theresa McDevitt ,  Shoba Shetty ,  Hong Xie

IPC: C07K16/28 ,  A61P35/04 ,  C07K16/30 ,  A61K9/00

Abstract: Bispecific monoclonal antibodies and methods for treating cancer are set forth herein.

公开(公告)号：US20210079115A1

公开(公告)日：2021-03-18

申请号：US16852371

申请日：2020-04-17

Applicant: Janssen Biotech, Inc.

Inventor： Theresa McDevitt ,  Shoba Shetty ,  Hong Xie

IPC: C07K16/30 ,  C07K16/28 ,  A61P35/00

Abstract: Bispecific monoclonal antibodies and methods for treating cancer are set forth herein.