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公开(公告)号:US20180319893A1
公开(公告)日:2018-11-08
申请号:US16037304
申请日:2018-07-17
Applicant: Janssen Biotech, Inc.
Inventor: McCarthy Stephen , Bernard Scallon , William Strohl , Susan Tam , Omid Vafa
CPC classification number: C07K16/32 , A61K2039/505 , C07K16/00 , C07K16/2887 , C07K2317/52 , C07K2317/524 , C07K2317/54 , C07K2317/70 , C07K2317/71 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/75 , C07K2317/92
Abstract: Antibody and other Fc-containing molecules with variations in the Fc region with reduced binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
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公开(公告)号:US20170204193A1
公开(公告)日:2017-07-20
申请号:US15463716
申请日:2017-03-20
Applicant: Janssen Biotech, Inc.
Inventor: William Strohl , Omid Vafa
CPC classification number: C07K16/32 , A61K38/00 , A61K2039/505 , C07K16/00 , C07K16/2887 , C07K2317/52 , C07K2317/524 , C07K2317/54 , C07K2317/71 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/92
Abstract: Antibody and other Fc-containing molecules with variations in the Fc region reduce binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
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3.
公开(公告)号:US20150118227A1
公开(公告)日:2015-04-30
申请号:US14597690
申请日:2015-01-15
Applicant: Janssen Biotech, Inc.
Inventor: William Strohl , Omid Vafa
CPC classification number: C07K16/32 , A61K38/00 , A61K2039/505 , C07K16/00 , C07K16/2887 , C07K2317/52 , C07K2317/524 , C07K2317/54 , C07K2317/71 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/92
Abstract: Antibody and other Fc-containing molecules with variations in the Fc region reduce binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
Abstract translation: 具有Fc区变化的抗体和其它含Fc的分子减少与Fcγ受体的结合并导致其活性,并可用于治疗各种疾病和病症。
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公开(公告)号:US20210155711A1
公开(公告)日:2021-05-27
申请号:US17150269
申请日:2021-01-15
Applicant: Janssen Biotech, Inc.
Inventor: Stephen McCarthy , Bernard Scallon , William Strohl , Susan Tam , Omid Vafa
Abstract: Antibody and other Fc-containing molecules with variations in the Fc region with reduced binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
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公开(公告)号:US10894836B2
公开(公告)日:2021-01-19
申请号:US16037304
申请日:2018-07-17
Applicant: Janssen Biotech, Inc.
Inventor: McCarthy Stephen , Bernard Scallon , William Strohl , Susan Tam , Omid Vafa
Abstract: Antibody and other Fc-containing molecules with variations in the Fc region with reduced binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
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公开(公告)号:US10053513B2
公开(公告)日:2018-08-21
申请号:US14818864
申请日:2015-08-05
Applicant: Janssen Biotech, Inc.
Inventor: Stephen McCarthy , Bernard Scallon , Susan Tam , William Strohl , Omid Vafa
CPC classification number: C07K16/32 , A61K2039/505 , C07K16/00 , C07K16/2887 , C07K2317/52 , C07K2317/524 , C07K2317/54 , C07K2317/70 , C07K2317/71 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/75 , C07K2317/92
Abstract: Antibody and other Fc-containing molecules with variations in the Fc region with reduced binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
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公开(公告)号:US09637549B2
公开(公告)日:2017-05-02
申请号:US14597690
申请日:2015-01-15
Applicant: Janssen Biotech, Inc.
Inventor: William Strohl , Omid Vafa
CPC classification number: C07K16/32 , A61K38/00 , A61K2039/505 , C07K16/00 , C07K16/2887 , C07K2317/52 , C07K2317/524 , C07K2317/54 , C07K2317/71 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/92
Abstract: Antibody and other Fc-containing molecules with variations in the Fc region reduce binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
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8.
公开(公告)号:US20150337053A1
公开(公告)日:2015-11-26
申请号:US14818864
申请日:2015-08-05
Applicant: Janssen Biotech, Inc.
Inventor: Stephen McCarthy , Bernard Scallon , Susan Tam , William Strohl , Omid Vafa
CPC classification number: C07K16/32 , A61K2039/505 , C07K16/00 , C07K16/2887 , C07K2317/52 , C07K2317/524 , C07K2317/54 , C07K2317/70 , C07K2317/71 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/75 , C07K2317/92
Abstract: Antibody and other Fc-containing molecules with variations in the Fc region with reduced binding to Fc gamma receptors and resulting activity and can be used in the treatment of various diseases and disorders.
Abstract translation: 抗体和其他具有Fc区变化的含Fc分子,其与Fcγ受体的结合降低并导致活性,并可用于治疗各种疾病和病症。
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